Sikandar Hayat Khan

71 Questions 338 Answers 0 Followers

Questions related from Sikandar Hayat Khan

Can some define the concepts of microbiome and microbiodata?

Yes, i read some data on google about these terms but not yet completely clear about this. Can some one help me understand what these terms are in simple language and how they are to be...

15 February 2019 8,338 5 View

What are the side effects of Botox?

While commonly use for beautification, but searching internet one can finds many side effects but still the market is growing fast. As i interpret it is Botulinum toxin used to reduce fine lines...

05 February 2019 1,075 31 View

What are phytochemical? What diets have them? Are they actually useful?

a term"phytochemicals" is used for various food products. I am not sure what these compounds are and why and how they are useful? And if they are useful, which diets have them?

25 December 2018 627 41 View

Should basic medical college training other allied medical specialties incorporate managerial sciences and information technologies?

The world is changing fast and lot many biotechnologies are now being routinely utilized by medical professionals in all domains. However, they do not have a formal training in this regard....

27 November 2018 734 21 View

How do you compare glucometer readings with lab gkucose results?

While both glcometer & lab glucose measuring technologies use different methodologies and sample. Still from physician to medic compare their results. What do you trust more & for what...

26 November 2018 5,290 6 View

Do you think electro-medical equipmnets are routinely calibrated in healthcare set ups?

Calibration of any electronic device is a mandatory step in achieving the desirable outcome. What do you say that your healthcare settings routinely calibrate their equipment to ensure patient...

19 November 2018 4,657 8 View

Any side effects of green tea?

Different kinds of green tea is now filling the shelves in marts. Everyone on the street will tell you something about the utility of this type or that type. Is it so insane or magic thing for...

18 November 2018 4,620 50 View

What is the importnce of magnesium in our body?

Magnesium as salts are being used in multiple diseases and sometimes being prescribed as just a supplement. There could be some side effects of over use of this nutrient and definitely issues...

23 October 2018 9,962 64 View

Should we as healthcare worker waer our white coats/hospital dress outside the hospital?

I believe we are spreading more infection and antibiotic resistance if we are taking/wearing our white coats (the trade mark of ant medic) outside hospital. Should we do that? Are we not spreading...

20 October 2018 9,440 14 View

If you are writing a mini review can you add a scematic from somebody's article after referencing?

This question is about writing a mini review where i want to add a schematic from some article after appropriate referencing.Can i do that?

15 September 2018 10,092 4 View

How do vitamin D affects immune response?

The effects of vitamin D are multiple & literature review indicates vitamin D almost being associated with many metabolic & non-metabolic disorders. Even someone told me that low vitamin D...

24 August 2018 1,831 22 View

Can you share your experience of using HbA1c in Diabetes diagnosis aongwith the kit/technology you use?

A1c is now routinely recommended for diagnosis of diabetes mellitus. However, I feel A1c variation owes a lot to patient & technology specific factors. So can u generally share our experience...

21 August 2018 4,124 2 View

What factors other than insulin resistance affect Polysystic Ovarian Syndrome?

Insulin resistance is considered as an important contributor, if not he sole cause of PCOS. But i believe there must be other tangible factors which cause insulin resistance. There are features of...

20 August 2018 6,881 4 View

Is it essential to measure IGF-1 and IGF-BP3?

There is some difference in protocols with regards to evaluation of IGF-1 measurements. Some lab just report IGF-1 and some do it by reporting IGF-1 with IGF-BP3. While i had some understanding...

16 August 2018 5,655 1 View

Why subcontinental population has more diabetes?

There seems to be alarming increase in type-2 diabetes in subcontinent. Can we have the possible attributives to this possible incoming menace?

11 August 2018 7,697 14 View

What are the differences between next generation sequencing (NGS) /2nd Gen and Third generation sequencing?

Apart from amplification requirements being mandatory for NGS, what are the other differences or advantages third generation sequencers like Oxford nanopore and PacBio provides? Which one is more...

07 August 2018 6,149 3 View

Should we have shorter read lengths in RNA sequencing?

While in general we desire to have higher coverage, implying higher read lengths in DNA seq to locate to cover the complete region on the DNA or to have overlap between read lengths. (Correct me...

03 August 2018 1,575 7 View

Difference between fasting htperglycemia and post-prandial hyperglycemia?

Fasting hyperglycemia and diabetes mellitus; In clinical laboratory practice I had seen so many cases of type-II diabetes mellitus who gets a diagnosis of diabetes mellitus based upon raised...

28 July 2018 4,079 3 View

Metformin response in type-2 diabetes mellitus: Role of gentics?

I was reviewing data glycted haemoglobin in patients with type-2 diabetes. Some patients seem to respond excellent metformin but some just do not did well. Yes i confirmed associated life style...

25 June 2018 461 15 View

How many variabiable we can add in SPSS variable view?

Good day i was wondering if there are like 1000 variables, can we add them in SPSS? Any web link or youtube video someone can refer me? Regards

17 June 2018 315 3 View

Are metabolic diseases linked with each other?

According to common soil hypothesis metabolic diseases are associated with each other due to underlying insulin resistance. What is your take on that?

01 January 1970 5,607 20 View

Which statistical software do you think easiest to operate by non-statisticians?

While I, most of the life have been using is SPSS, I wonder is there any other software which can be used by people who are non-statisticians What software do you suggest?

01 January 1970 1,584 27 View

Is there a way to calculate personal impact factor of an author/researcher?

01 January 1970 9,747 10 View

Anbody being aware of/knowledge of/ done single molecule sequencing?

While we started with PCR to sanger seq to now in vogue NGS. But now heard of single molecule sequencing. Can someone commet on this type. Anything is welcome on this topic Regatds

01 January 1970 7,687 7 View

Diabetes a modern day plague: Any solutions, suggestions or comments

Diabetes, especially type-2 diabetes mellitus is fast evolving as a major source of mortality and morbidity. What do you want to say to avoid this present era curse in our society?

01 January 1970 6,925 24 View

Are you invited to write an editorialfor a journal?

Are you invited to write an editorial for a journal? OR you can submit one of your own to the journal you want to submit.Anybody who guide me here

01 January 1970 7,748 2 View

What is the most disturbing thing you like in a medical set up as a patient?

While patient satisfaction parameters are multiple, but still it is important to learn what is the most disturbing thing to a patient once he enters into a medical facility

01 January 1970 9,707 16 View

Daily Plate of Fried Chicken Tied to Higher Risk of Premature Death: Comments please.

Reference: https://www.medscape.com/viewarticle/908396?src=wnl_edit_tpal&uac=104521MY&impID=1873365&faf=1 According to Medscape: " Women who eat fried chicken every day may be 13...

01 January 1970 1,349 11 View

Comments on Aspirin resistance: your experience please

Dear ALL Some people using aspirin as loprin or other coated formulations with underlying ASCVD(Atherosclerotic cardiovascular disease) still end up having accelerated atherosclerotic diseases....

01 January 1970 885 4 View

How to make a general assessment of glycemic index of any food?

Glycemic index probably provides us with an idea abort how much a food raises our sugar level. Can we a rough estimate of glycemic index of the food which we eat. I s there any simple way to do that?

01 January 1970 1,238 9 View

How to behave in a hostile & unfamilar place?

Not sure whether the question is right or wrong but just wondering opinions once faced with odds, how to behave

01 January 1970 8,646 38 View

Is mobile use is hazardous to our bodies?

If YES, then how? And to what limits we should be utilizing these gadgets. Whatsapp post shows a lot of damage to brain and other body organs. Definitely there are some radiation. Are there any...

01 January 1970 5,222 23 View

What should be ideal doctor population statistics and nurse to population statistics:What gap you face in your countries?

Optimal healthcare coverage is highly dependent upon medical and paramedical human resource. While multiple surveys do demonstrate some statistics on that as targeting differently by different...

01 January 1970 8,828 13 View

What is the difference in cis and trans type of fatty acids: which one is better and what should be avoided ?

While for sometime now we had been hearing about polyunsaturated as good fats and saturated as bad ones: please correct me for this if i am wrong now we have varieties within unsaturated fatty...

01 January 1970 8,949 14 View

Flu vaccine: How effective is this?

Each year flu takes many of us on to cause sickness, loss of technical man hours and sometimes mortality in the older and younger. The viruses change every year and i am not sure the vaccine...

01 January 1970 7,672 17 View

WHO to Create Global Advisory Panel on Human Gene Editing: Do we need oversight on such activities?

Chinese claim editing genes of 2 babies to make them resistant to HIV. "World Health Organization (WHO) is creating a global panel to study human gene editing and the scientific, legal, social,...

01 January 1970 8,496 18 View

Aspirin for Primary Prevention-New Meta-analysis: Does aspirin help in reducing heart attacks and strokes?

Ref: https://www.medscape.com/viewarticle/908161?nlid=127396_2201&src=WNL_mdplsnews_190125_mscpedit_honc&uac=104521MY&spon=7&impID=1868713&faf=1 Medscape " A review of the...

01 January 1970 5,160 5 View

Fever is good for immune system: so should we try to reduce fever?

Ref: https://www.news-medical.net/news/20190124/Training-heart-cells-in-culture-to-mimic-human-cardiac-tissue.aspx New research says that fever help immune response to boost by allowing more...

01 January 1970 7,983 37 View

What about this style of cholesterol testing? Will that benefit or just waste of money?

Its been time that sub-classes of both LDL and HDL are there and some even market them. Can you offer your comments on this style of testing of lipids/cholesterol or the traditional markers are...

01 January 1970 7,401 24 View

Should first aid including basic life support be taught and practiced as a compulsory subject from school life?

The first person who reach the site of trauma, or to see a heart attack patient or everybody living with a possibility of facing a major disaster anywhere and anytime is inevitable. Poor primary...

01 January 1970 4,200 37 View

Hyperuricemia and IQ: Is there a link?

Dear ALL I just need your experiences, evidence if any to support or refute regarding the possible link between raised uric acid levels and intelligence.

01 January 1970 7,820 8 View

Over the counter medications: Should these not been regularized

There are so many vitamin supplements and other drugs which many countries you can get without medic’s prescription. What are your suggestions on this topic? Many medication if used long-term can...

01 January 1970 9,336 16 View

Cholesterol particle size rather than concentration? a concept change

Over the years most studies have found that the smaller LDL particle size are considered to more atherogenic and can cause more CVD than large LDL particle sizes. Moreover, subcontinental...

01 January 1970 8,661 25 View

What is the role of aspirin in primary prevention of cardiovascular disease inpatients with diabetes mellitus?

ASCEND trial from UK has found no benefit of aspirin preventing heart attacks or stroke in their 7.4 years long placebo-control trials? what is your say?

01 January 1970 9,278 24 View

When and if to start lipid/cholesterol screening?

Excessive blood cholesterol implies a future risk for atherosclerotic thromoeboembolic risk diseases like heart attack and stroke and exacerbate problems related to hypertension and diabetes....

01 January 1970 4,138 10 View

According to Medscape, More Evidence Ties Diet Drinks to Greater Stroke Risk: What are your opinion on DIET DRINKS?

Reference: https://www.medscape.com/viewarticle/909395?src=wnl_edit_tpal&uac=104521MY&impID=1891813&faf=1 DIET DRINKS are being more and more preferred over energy drinks with the...

01 January 1970 2,111 4 View

Vitamin B12 deficiency and heart disease: Do we have meat as a nutritional source?

Does b12 deficiency cause heart diseases? Regards

01 January 1970 5,045 20 View

Medscape reports "Obesity to Blame for Almost 1 in 20 Cancer Cases Globally": How do you link obesity with cancer? Kindly have your say

Ref: https://www.medscape.com/viewarticle/906881?nlid=126850_2049&src=WNL_mdplsnews_181228_mscpedit_imed&uac=104521MY&spon=18&impID=1846364&faf=1 Obesity is the plague of...

01 January 1970 4,219 18 View

WHO data: The number of people with diabetes has risen from 108 million in 1980 to 422 million in 2014. Any novel idea to address this?

Ref: https://www.who.int/news-room/fact-sheets/detail/diabetes Diabetes, as I interpret is one the leading causes of mortality and morbidity across the globe. While awareness does exist but still...

01 January 1970 8,234 40 View

Why Mosquitoes prefer some people over others: Genetic discovery

A new study has tried to assess the genetic variants among mosquitoes that make them more susceptible to spreading deadly viral diseases such as dengue, yellow fever, Zika and chikungunya and more...

01 January 1970 6,585 23 View

Hospital waste management

Starting from personal & patient safety issues within hospital in terms of widespread emergence sntimicrobial infections, infections affecting the hospital staff to now acquiring a community...

01 January 1970 5,140 7 View

INSOMNIA: Does it have any metabolic or psychological consequences

Some people are unable to sleep saying that its too difficult to sleep. End up using sleeping pills and may be a little dependency. However, in practical life they behave normally. Can insomnia...

01 January 1970 938 41 View

There is no medicine like exercise. Your comments please

I believe exercise is the best health tonic, which is just available to everybody and mostly everywhere. No medic needed, cost effective.

01 January 1970 2,761 26 View

Haunting mankind....the cholesterol: what about new PCSK9 inhibitors or the old STATINS?

Statins though routinely be used, but are having multiple side effects with trademark "muscle aches". While that is probably known for statins but new PCSK9 inhibitors may not be that innocent, I...

01 January 1970 8,466 5 View

Lab on chip, MRI in hand: Do you think technology miniaturization will lead us to this?

Biotechnology is fast revolutionizing, changing and becoming miniaturized by every single second. Do you agree we will see such a boom in biotechnology inn next few years

01 January 1970 5,721 9 View

How do you diagnose gestational diabetes melltus in your country?

Gestational diabetes mellitus is type of diabetes first detected or appearing during pregnancy. Different criteria over the years have appeared to diagnose this condition. Can you share your...

01 January 1970 3,412 33 View

How common is hepatitis in your cities or regions where you live in?

HCV is common and there is no vaccine protection? so just being comparative here to know how common and lethal is this virus in your societies? How you are managing its primary prevention? regards

01 January 1970 1,806 16 View

Nutritional genomics: How important is this concept?

Reference: https://www.news-medical.net/life-sciences/What-is-Nutritional-Genomics.aspx Nutritional genomics is the study of nutrition and its relationship with the genome. The ability of the...

01 January 1970 5,440 17 View

Artifcial human wombs and designer babies: Do you thinkits going to be reality?

Dear ALL While fiction already shows it in movies, animal experiments have been completed, gene editing is becoming real do you recommend/suggest designer babies and babies being homed in...

01 January 1970 7,645 6 View

Anybody aware ofdefining criteriafor "FAMILIAL COMBINED HYPERLIPIDEMIA"?

The "FCHL" is so commonly used in hospital setups but i am not aware of the EXACT defining criteria for "FAMILIAL COMBINED HYPERLIPIDEMIA"? Can anyone provide me the reference? or a guideline...

01 January 1970 9,570 11 View

How to best deal with the pandemic of obesity?

Obesity is becoming a common problem in almost all developed countries. From life style to medicated and non-medicated medicines are all available in market? What is your best advice to curb this...

01 January 1970 9,025 37 View

Platelet rich plasma: How useful it is?and are there any regulatory guidelines on preparation of this PRP?

These days PRPis almost used in multiple diseases from athletes, to hair growth acceleration, joint pains and so many other conditions. Ca someone throw some light and provide any guidelines on...

01 January 1970 8,114 7 View

Do we actually need anti-microbial agents and anti-skeptics for wound management?

Ref: https://www.medscape.com/viewarticle/904991?nlid=126941_3243&src=WNL_mdplsfeat_190108_mscpedit_imed&uac=104521MY&spon=18&impID=1854956&faf=1 From Medscape: "Antimicrobial...

01 January 1970 3,318 20 View

What about male's end of fertile life, the andropause: Is it for real or just a deficiency state of hormones?

Andropause to me is a kind of decline male sex hormones,which could be either very late or early but not sure much about this.If it is come, what is the probable age?

01 January 1970 1,235 3 View

Consuming Ultra-processed Food Tied to Higher Mortality: Comments please.

Medscape article says ultra processing of food is associated with higher mortality. "Findings from this prospective study of a large French cohort suggest for the first time, to our knowledge,...

01 January 1970 452 5 View

"Jumping genes"....the Alu element: Can someone elaborate more on this subject?

While reading i came across these Alu elements which are in other ways termed as jumping genes. This seem to be real concept changer for me. Anybody who could elaborate more on this? Regards

01 January 1970 1,244 11 View

Hungry or healthy: Are there benefits of being hungry (fasting)?

Ref: https://www.medscape.com/viewarticle/898953?src=WNL_infoc_190102_MSCPEDIT&uac=104521MY&impID=1850565&faf=1 Medscape news suggests fasting is good for both in terms of both...

01 January 1970 4,385 55 View

Brain-computer interface: A computer that can read your mind?

Nick Lavars, 2017, Rise of the mind-reading machines [online]. Available at: http://newatlas.com/mind-reading-machines-musk-future/48642/. Accessed 05.30.2017 As I moved thru this article, I...

01 January 1970 4,556 24 View

Please have yoursay on Cystatin C and cardiovascular disease and neurologial diseases?

Ongoing with my previous discussion topic I have found data linking Cystatin C being associated with neurological conditions like Alzheimer's disease and cardiovascular disease apart from being in...

01 January 1970 3,504 0 View

Are there any side effects of "stem cell therapy"?

Stem cell therapy is seeing its boom and most of the literature i reviewed only positive side of this panacea like solution. Are there actually any side effects? regards

01 January 1970 1,467 16 View

Anyone having practical or better idea/experience of using Ocotype Dx in breast or colorectal cancer prediction?

Ocotype Dx for breast cancer is 21 gene signature model with 5 house keeping genes and other genes associated with other carcinogenic properties to provide a net score of cancer risk. Anyone...

01 January 1970 6,705 4 View