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Questions related from Mostafa Elsersy
Someone was taking Daflon 500 mg (450 mg Diosmin, 50 mg Hesperidin) twice daily for her varicose veins. Now, the manufacturer makes Daflon 1000 mg (900 mg Diosmin, 100 mg Hesperidin). Now, the Q...
06 November 2022 5,593 4 View
Is it after reaching the steady state concentration (3-5days) or it may take more days to reach the maximum effect for atrial fibrillation control?
20 April 2018 1,313 11 View
Aren't we suppose to see the peak effect after 4-5 half lives of the drug? After reaching the Css? I did view the drug monograph, and it states that the peak effect is seen after 6 hrs not after...
06 April 2018 7,204 7 View
Which agent is the best for occasional use for someone who has NAFLD ? and why ?
23 February 2018 9,551 15 View
There are contradictory data, two references are attached. What would be your decision ? Recommend it or not ?
17 February 2018 5,234 6 View
Isn't Css the same as the plasma therapeutic level ? Because if so, in the case of Acetaminophen, just one dose of 500 mg would reach the Css, and there would be no need for 4-5 half life ? if...
11 February 2018 3,945 4 View
Do all drugs need to achieve the steady state concentration after 4-5 half life in order to see the therapeutic effect ? Doesn't ibuprofen produce its effect from a single dose without 4-5 half...
07 February 2018 7,312 17 View
Take this example (Bisoprolol is the mentioned example ) : assuming that 5 mg is the minimum effective dose dosing with 5 to 20 mg, and mean peak values range from 16 ng/mL at 5 mg to 70 ng/mL...
07 February 2018 4,332 3 View
I have researched, and there are many available ways to manage cough in community pharmacy setting, so which resource or reference do you use ?
28 January 2018 3,070 12 View
I'd like to know the best published reference for differential diagnosis of cough ?
28 January 2018 5,761 3 View
I have researched, and they are used interchangeably, so I'd like to know if there is any paper or article that can illustrate the difference between both on the molecular or cellular level ?
25 January 2018 1,668 3 View
I think asking and formulating questions have a big impact on our lives, so I was wondering what techniques do you use to formulate your questions, and how much time you set for formulating the...
11 January 2018 5,189 6 View
Is it just you go check graded dose response curve for comparing different pharmaceutical agent ? Or there is another fast quick method ? Lets say you want to give the most available otc analgesic...
07 January 2018 5,484 9 View
I'd like to know the correct numbering of atoms within large heterocyclic molecule, and the nomenclature of parts of it, so when I select a portion of the compound I can know what is the IUPAC...
05 January 2018 7,484 13 View
In this scenario, I'm interested in Daflon (Trade name). Could misdiagnosis be harmful and turn the Pharmacological and therapeutic effect of a drug (Daflon) into an adverse reaction? We know that...
01 January 2018 9,485 2 View
What is your view on toxicology after being in the field? What principles do you see as the most important?
31 December 2017 840 4 View
I'd like to know how far should I go with regard to the effect? For example, we know that bisoprolol reduce the heart rate, so, lets assume this is the only known effect that has been shown...
13 December 2017 6,820 8 View
What is the best online database for anatomy in order to interpret articles and visualize details in a good models?
03 December 2017 5,310 9 View
Cetirizine is more toxic than Bisoprolol according to hodge and sterner scale, and yet Cetirizine is available as OTC drug, and Bisoprolol is a prescription drug! Any insights?
24 November 2017 934 7 View
Where can I find the toxic dose(Not the lethal dose) of Bisoprolol? What reference do you use? Do you rely on overdosage cases? And if so, can you give me any reference for the toxic dose of...
16 November 2017 3,182 3 View
or the drug could be harmful with no apparent adverse reactions and the bad effects appear after chronic use?
23 October 2017 2,382 7 View
How can I view the side effects of any drug and make sense of it, and gather some insights? Will I have to know the adverse drug reaction type? Or the frequency of the reaction?
20 October 2017 2,376 7 View
20 October 2017 1,488 2 View
Will classification of drugs adverse reactions into groups A, B, C, etc.. will give me insights into their safety and comparing their toxicity? Like here in the case of ibuprofen, classifying...
17 October 2017 7,134 7 View
Which parameters are the most important and that I should check when comparing safety of two drugs?
06 October 2017 5,736 3 View
How should my study in Pharmacology be, to be an expert in Pharmacology? Read more experiments, study more mechanisms or what?
01 January 1970 2,054 5 View
Best resource available to check the ways of transmission of microbes, pathogenesis, and details about the microbe?
01 January 1970 774 12 View
Nearly 50,000 died of opioid overdose during 2018. What I want is, textbook or research paper that go deeper into these numbers and analyze them. Like, were all deaths attributed to overdose due...
01 January 1970 9,829 4 View
Statistics that I have found so far with regards to opioid overdose aren't differentiating between unintentional vs intentional overdose. Like this stat, which mentions about 50,000 deaths were...
01 January 1970 8,655 7 View
If I want to be up-to-date with the most recent public health info.like major outbreak, new intervention techniques, warnings, etc..which resources/websites do you recommend and I should check daily?
01 January 1970 8,566 20 View
Is there any website that can tell me when this adverse reaction will occur? For example, will this adverse reaction occur after repeated exposure? Or can occur after first dose? Or can be delayed?
01 January 1970 3,566 3 View
The operation (Vaginal Hysterectomy) took place 14 days ago, and she will undergo K.U.B scan (Radiology procedure) and she is wondering if taking castor oil (oral) will affect her negatively?
01 January 1970 3,762 2 View
When do you go the medical literature (primary - journal articles) instead of going to well known databases like Lexicomp, PDR, etc..with regard to adverse reactions/effects? Is it when you check...
01 January 1970 5,348 5 View
Medical History: 53 Y F, last degree prolapsed uterus presents with four ulcers, 2 on the surface of the uterus, one on the surface of cervix and another one (Can't recall the location). There is...
01 January 1970 3,358 10 View
When you prescribe a medication, what is your go-to-site/book/reference to check for adverse reactions? And what type of adverse reactions do you check? Is it type A adverse reactions only that...
01 January 1970 4,187 4 View
Excuse my naive experience in this area. Lets assume we have a patient with 2nd degree hemorrhoids, and we want to apply topical product to reduce the swelling of hemorrhoids, do we apply the...
01 January 1970 4,868 12 View
Extroverts tend to be friendly and remove barriers during communication unlike introverts who "keep others at a distance". Is there any scale that can measure verbal and non-verbal cues of...
01 January 1970 413 3 View
How can a patient safely taper off bisoprolol 2.5 mg who used it once daily? What schedule can he follow to taper off gradually? Any reference/paper/textbook for doing this?
01 January 1970 5,576 10 View
Any research paper or review that discuss pharmacological treatments for voice and speech disturbances that occur as a result of anxiety? For example stuttering, weak/trembling voice, etc.. as a...
01 January 1970 3,402 3 View
Am I getting this correct? Is Diosmin better than Rutin in the following parameters: Oedema, Oedema (mm), Heaviness, Paraesthesias and adverse events? Also, is Rutin better than Diosmin in the...
01 January 1970 6,352 1 View
Do you discount if a consumer ask for a discount? And if so by how much? And is there a difference between customers in terms of the discount strategy? When you answer, please support your answer...
01 January 1970 3,833 9 View
When I viewed the PK parameters of both warfarin and candesartan, I found that both medications have 99% plasma protein binding. I then went to check and confirm there will be PK interaction...
01 January 1970 3,676 4 View
What will happen if the patient used carbamide peroxide to remove earwax when there is dizziness? I know dizziness could indicate inner ear problem, but what if the patient used carbamide peroxide...
01 January 1970 840 4 View
