In your opinion, what are the most important toxicological principles ?

More Mostafa Elsersy's questions See All

What are the shear and normal stiffness values of an LLDPE liner in 3D numerical modeling of a stockpile?

I am seeking experimental or applicable data for the liner (LLDPE) interface in FLAC3D numerical modeling of a large stockpile. Could you please recommend suitable references? The preferred data...

05 August 2024 3,665 0 View

Do you know any references for analyzing stochastic fiber orientaion composites ?

Hello everyone I am looking for one or some books for propertes and behaviors of stochastic fibre orientation composites. unfotunately I could not find any suitable reference for thias by...

04 August 2024 3,461 3 View

What is the recommended safe distance between drilled holes in fiberglass, and which standard governs the drilling process?

Material : Fiberglass sheet thickness : 3mm

03 June 2024 6,255 0 View

What is the simplest way to introduce a heterostructure??

The best definition of heterostructure.

16 May 2024 9,848 1 View

Nanoparticles zeta potential ?

Is there any mathematical relationship between zeta potential and both the polydispersive index (PDI) and pH of the zero-point charge of the nanoparticles?

28 April 2024 8,728 5 View

How can we create these plots?

how can we create these plots? a 3-dimensional look and showing strength with colour, which software does create these pictures? source of image: Directive giant upconversion by supercritical...

02 April 2024 9,999 4 View

Is it possible to grow graphene on the vertical wall of a structure, for example on the vertical walls of a SOI waveguide?

09 March 2024 1,990 2 View

What is the impact of shopping mall architecture designed on consumer's behavior?

does architectural designe influence the consumers attitudes and their intention to shop and buy.

05 March 2024 7,975 5 View

How can I convert files formate from (.spu)into (.CNF) ?

There are many applications that used for gamma spectral detection and analysis but some of them are more suitable for me in detection usage and others in analysis usage and these applications...

01 March 2024 5,459 0 View

I have a question related to power analysis and inferential statistics?

Can anyone here me with one biostatistics question. It is about finding the sample size from power analysis. I have the variables. Just need an assistance with the calculations.

12 February 2024 5,763 7 View

For an in-vitro drug release study, what molecular weight cut-off (MWCO) dialysis bag is required for a 117 kDa protein?

kindly reply me. Thanking you in advance.

05 August 2024 7,727 4 View

What Are the Best Alternatives to the MTT Assay for Assessing Cell Toxicity of Colored Herbal Extracts?

I am currently investigating the cytotoxicity of a series of herbal extracts, and like many studies, I have been using the MTT assay to evaluate cell viability. However, I am encountering a...

31 July 2024 193 4 View

Inquiry on Maximum Nucleic Acid Volume for 2.5 mL Liposome Solution?

I am currently working on a project involving liposomes and need to determine the maximum volume of siRNA that can be added to a 2.5 mL liposome solution with a total lipid concentration of 10...

30 July 2024 6,420 1 View

How can I measure arsenic concentration in a patient blood?

I intend to get an economical and accurate LAB TEST to measure arsenic concentration in blood sample.

23 July 2024 3,654 2 View

What is the suitable solvent of MIL-100 for chemotherapy?

I synthesised a nanocarrier by conjugation MOF (MIL-100) with folic acid for use in chemotherapy but the samples didn't dissolve completely in aqueous solution or DMSO. Instead, they only...

19 July 2024 8,522 0 View

How to extract binding energy from pv.maegz file without using Schrodinger?

I have conducted virtual screening using Schrödinger on a database of 17,000 molecules. Unfortunately, I cannot use the system with the Schrödinger license at the moment. I am trying to find a way...

18 July 2024 2,881 4 View

Use of NC or NTC to descibe negative control?

Hello, I would like to ask which is the best terminology to use for describing a negative control in an experiment (drug testing in-vitro, viral infection): NC (negative control) or NTC? Thank you...

18 July 2024 4,183 2 View

What is the suitable solvent of MIL-100 for chemotherapy?

I synthesised a nanocarrier by conjugation MOF (MIL-100) with folic acid for use in chemotherapy but the samples didn't dissolve completely in aqueous solution or DMSO. Instead, they only...

15 July 2024 2,414 1 View

How to calculate percentage cumulative drug release?

How to calculate percentage cumulative drug release when, Total volume of dissolution media = 250ml Added formulation was equivalent to 10mg of drug Sample withdrawn = 1ml each time Sink condition...

15 July 2024 4,192 1 View

Abnormal data in in-vitro drug release study?

I'm doing in-vitro drug release study using dialysis bag method and collecting samples from the external medium at several time points, subjecting to UV-Vis spectrophotometry. But my absorbance...

14 July 2024 6,829 2 View

Zhi Xiong Chong

Types, concentration and duration of toxins exposure and availability of a suitable antidote are several important toxicological principles.

Peter H. Roos

- To clearly identify the molecular target(s) of a toxin.

- To define the dose response relationships with respect to different endpoints.

- To recognize long-term effects of compounds.

- To define effects (additive, synergistic) of chemicals in mixtures (binary and more complex)

- To recognize variability in response to toxins influenced by the genotype.

Mostafa Elsersy

Thanks Zx Chong !

Thanks Dr.Peter!