In your opinion, what are the most important toxicological principles ?

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Zhi Xiong Chong

Types, concentration and duration of toxins exposure and availability of a suitable antidote are several important toxicological principles.

Peter H. Roos

- To clearly identify the molecular target(s) of a toxin.

- To define the dose response relationships with respect to different endpoints.

- To recognize long-term effects of compounds.

- To define effects (additive, synergistic) of chemicals in mixtures (binary and more complex)

- To recognize variability in response to toxins influenced by the genotype.