I see some Healthcare Professionals recommend Coenzyme Q10 supplementation because Beta Blockers deplete it. I tried to find evidence for this, and I didn't find except this paper.
Article Bioenergetics in clinical medicine. III. Inhibition of coenz...
So my Q, as a Pharmacist, do I have to supplement someone who is taking Bisoprolol or not? Because I didn't find also Bisoprolol mentioned in this paper.
Clinically significant Coenzyme Q depletion does not happen with Bisoprolol or any other cardioselective beta blocker. There could be some insignificant depletion of Coenzyme Q with propranolol. Anyway, there is no indication for Coenzyme Q supplementation with any beta blocker.
Hi Mostafa,, I totally agreed with answar of Dr Koshy. There are some suggestions that propranolol may reduce level of Co enzyme Q. But supplementation is not required. Bisoprolol is very unlikely to cause Co enzyme Q depletion. Following article might help you... Thanks
Thanks a lot Dr. A. George Koshy & Thanks a lot Dr. Biswajit Majumder
Hi,
Coenzyme Q10 might be added as an adjunct to the antihypertensive therapy as it helps to reduce the dose of antihypertensive drugs. Please refer the following articles...Thanks
Article Coenzyme Q10 in the treatment of hypertension: A meta-analys...
Article Coenzyme Q10 in cardiovascular disease
https://www.sciencedirect.com/science/article/pii/009829979490037X
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