We know that natural products aren't regulated by the FDA, so when checking the safety of natural products/Herbs, should I check for adverse reactions and toxic dose only? Or should I also check for carcinogenic capability? Or carcinogenic capability will be listed as a default under adverse reactions? (I mean whether this product is carcinogenic or not)
"Natural products" is general. The check for different adverse effects is related to each specific natural product and its in vivo use.
As you know, an important number of pharmaceuticals are originated from natural products. The tests realized for safety take lot of time and money. Therefore, the choice of analyses should be significant.
There is no general protocol for all natural products for adverse effect evaluation.
Natural products are a very important class of medicinal drugs. Roughly 25% of all drugs are derived from natural sources. For your particular product, a good starting point would be the products history. If people have been taking this product for many centuries (eons?), then the risk of adverse effects is very low. However, standard toxicity tests and carcinogen tests should be performed. Beyond this, I would recommend testing for heavy metals and persistent environmental toxins (pcbs, etc.). Also, there are requirements in the US for vitamins (not sure how much supplements apply). These are listed in the DSHEA standards.
Quality of Natural Health Products Guide
https://www.canada.ca/en/health-canada/services/drugs-health-products/natural-non-prescription/legislation-guidelines/guidance-documents/quality-guide.html
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