91 Questions 43 Answers 0 Followers
Questions related from Ammar Bader
Is there any anti-cancer drug taken by inhalation for the treatment of human lung carcinoma (A549), what are the most suitable characteristic properties for drugs administered by inhalation? which...
06 June 2019 433 3 View
Microorganism produce their own antibiotic, could they change the type of antibiotic to face some challenges such as stress or the growth of other microorganism in their growing media or to...
02 February 2019 5,961 1 View
I found a beetle that emits a bad smell. I would like to extract it in order to isolate possible pheromones. What is the solvent of choice suitable to suppress the insects before homogenizing...
12 December 2018 2,728 0 View
Are the biosynthetic pathways of cantharidine disclosed or not?
11 November 2018 8,377 0 View
I have very limited knowledge in the identification of insects, Would you please identify this insect attracted by Tephrosia nubica growing in Saudi Arabia?
11 November 2018 4,410 3 View
What is the most official source for plants botanical name, I encountred a problem with the name of plant species called Hypoestes forsskaolii (Vahl ) R.Br. (according to www.theplantlist.org )...
10 October 2018 1,417 3 View
Parathyroid Hormone is good for osteoporosis in certain circumstances, it is warned that such therapy could cause bone cancer!!! Parathyroid Hormone is good for bone and may cause osteosarcoma,...
10 October 2018 9,806 1 View
Are there LH and FSH antagonists available as drugs that could attenuate the precocious puberty?
09 September 2018 2,169 0 View
There is a relationship between smoking and Parkinsonism , could MPTP be a degradation product of Nicotine.
08 August 2018 1,462 4 View
I have read about multiple sclerosis and I was very surprized that no medication is available for this disease! Mayo Clinic stated " There's no cure for multiple sclerosis. However, treatments...
03 March 2018 1,377 11 View
Which factors trigger the glycosidation of flavonoids? is glycosidation a genetical pattern or influenced by exogenic factors?
02 February 2018 6,242 1 View
some journal with open access ask high fees to publish an article, this cost can reach up to 2500 $ USA, is it logic to charge this high cost on the author who has paid a lot of costs to...
01 January 2018 7,511 35 View
Many plants became rare or endangered due to many factors among them urbanization, overgrazing and climate change. what is the most important priority to do? 1- protection of the...
01 January 2018 4,815 3 View
Kynureninase is an interesting enzyme involved in many diseases such as schizophrenia and viral diseases, is these a synthetic ligand that can be used to compare the activity of certain...
01 January 2018 6,913 1 View
In nature there are very few natural compounds with anthelmintic properties, what is the best guideline for the selection of natural compounds to be screened as anthelmintic drugs? what are the...
11 November 2017 2,252 4 View
Adding plants extract in some antimicrobial assay could lead to the formation of crystals, how can I prevent in general the formation of crystals?
11 November 2017 8,840 1 View
I have visited many historical botanical gardens, but I think that the situation is not one of the best, what are the most serious concerns that face the existence of these botanical gardens? how...
09 September 2017 2,284 14 View
D-ribose has demonstrated significant enhancing abilities in replenishing deficient cellular energy levels following myocardial ischemia, does the metabolic pathway differ from that of D-glucose?...
09 September 2017 2,808 2 View
many patients receive anti-cancer medication after tumoral metastasis, what is the expectancy to survive? is it logic to administer anti-tumoral drugs in this case? are there scientifically proven...
09 September 2017 5,664 1 View
What is the mechanism of action of Clomipramine "Anafranil" used for the treatment of nocturnal enuresis?
07 July 2017 718 3 View
could osteopetrosis "stone bone or marble bone disease" be treated by chemical agents that cause osteoporosis such as corticosteroids.
07 July 2017 8,282 3 View
Modern medicine insists on curing patient who has cancer with sophisticated and expensive drugs. but statistics say these drugs can prolong the life for several months but with a lot of suffering,...
06 June 2017 4,362 4 View
I am looking to know the IC50 of podophyllotoxin in MCF-7, HeLa or other cell lines, in literature I found as positive control etoposide or teniposide but never the podophyllotoxin.
05 May 2017 3,765 3 View
I found this plant in a Saudi Drugstore, I have no idea about its origin or scientific name can you help me in the identification of this plant.
04 April 2017 5,084 10 View
I found this plant in a Saudi drugstore, it looks as Terminalia chebula but I not sure 100%. Please help me in the identification of this plant !!
04 April 2017 7,385 4 View
In flow cytometry analysis of propidium iodide (PI) stained nuclei, if the cell arrest occurs in G0/G1 phase which are the most important enzymes involved in this phase? Is there a cascade enzyme...
01 January 2017 2,590 3 View
some small natural molecules have huge number of biological activities, such as Thymoquinone, Linalool, carvacrol "monoterpenes", quercetin, luteolin "Flavonoids"? What makes them interactive with...
01 January 2017 3,829 1 View
I found this Jatropha as a cultivated plant in my university campus, I am not sure if it is Jatropha glauca.Please help me in the identification of this plant.
12 December 2016 1,664 12 View
Please if you have the experience in the isolation and characterization of polysaccharides you can share in a project grant and in publication, The mushroom in question has a very good anticancer...
12 December 2016 8,918 2 View
dealing with natural drugs in small quantities (10 to 100 mg) in chemical reaction is very risky, in many cases the reaction does not occur causing the loss of hardly isolated natural compounds....
10 October 2016 5,203 3 View
publishing scientific articles has well known criteria for each scientific journal, some ambitious authors make a good scientific but not very brilliant work, in many cases their work is rejected...
05 May 2016 5,635 8 View
Plagiarism control is a good tool to protect the journal quality, recently it became a nightmare for the authors who cite their own work, even material and methods are sometimes subjected to...
05 May 2016 7,613 7 View
I prefer to re-use the solvents after their evaporation and recovery, but sometimes the percentage of these solvents is changed after their recovery. for example, if I use chloroform and methanol...
05 May 2016 908 10 View
unfortunately I do not have a free access to planta medica, can any one please send the PDF format of: Eloff, J.N., 1998. A sensitive and quick microplate method to determinethe minimal inhibitory...
05 May 2016 1,926 2 View
I use the website www.theplantlist.org to obtain the exact correct botanical name of the plants. But sometimes I find the phrase "is unresolved name" for certain species, How can I guarantee the...
04 April 2016 2,921 5 View
I wish to perform anti-microbial test with diffusion method in agar using methanolic plant extracts, can I use pure DMSO to dissolve these extract to overcome the solubility problem of these...
02 February 2016 8,124 33 View
I have a semiprep system of Water, the loop volume 100 µl, can i inject 90 µl as maximum volume of my mixture?
02 February 2016 6,413 4 View
Is it possible to perform Beckmann rearrangement for aethiopinone (1,2 diketone derivative)? Could the aromatic ring be obstacle the rearrangement? please check the attached proposed reaction.
01 January 2016 8,104 8 View
I would like to measure the attractive and the repellent effect of certain essential oils, is there an apparatus or a well known method to perform this experiment?
01 January 2016 5,146 9 View
how can I calculate the synergism between 2 active compounds? is there a mathematical equation? If compound A has EC50 = 10 mg and compound B has EC50 = 40 mg, what is the logic concentration to...
12 December 2015 4,081 7 View
some data suggests that the GABA receptor includes a portion for benzodiazepine receptor, what is the natural ligand for this receptor?? as all receptors in our body have a natural ligand which...
11 November 2015 8,292 9 View
I am looking for international conferences on natural products, unfortunately some conferences are not sufficiently publicized or announced to late!! is there a permanent websites which announce...
11 November 2015 485 7 View
Alzheimer's disease is caused by the lack of the neurotransmitters acetylcholine and glutamate, is this lack is due to the deterioration and death of brain cells? what is the best way to contrast...
11 November 2015 1,604 3 View
in SciFinder 3157 papers and patents are published on ivy, but no study was conducted for pregnancy. but I found one article "Ethnoveterinary medicines used for ruminants in British...
11 November 2015 2,271 6 View
first generation of antihistaminic drugs have sedative effect as side effect, some doctors prescribe these drugs for hyperactive newborn, what are the advantages and risks.
09 September 2015 9,585 2 View
I found in literature very few natural drugs used as orphan drugs (mainly enzymes)...the majority is synthetic drugs. is there an article which lists the natural orphan drugs.
09 September 2015 9,722 4 View
glycosides are metabolized mainly in the intestine by enzymes of human and normal flora, is there some cases of absorbed flavonoid glycoside without the cleavage of the glycosidic bond? which...
09 September 2015 1,345 7 View
I found this plant in the garden of my friend, I am unable to identify it, please help me in identifying this plant. Its flowers is similar to those of Magnolia.
06 June 2015 8,395 11 View
is it possible to perform a mixed culture between Pseudomonas aeruginosa or Acinetobacter baumannii and a yeast? how it is possible to monitor mixed culture and to shift the favorable conditions...
02 February 2015 4,562 10 View
some tumors are considered more aggressive than others and not resopnding to chemotherapy, according to the international statistics: which is the most agressive type of tumor with lowest...
12 December 2014 1,055 6 View
although plant tissue and cell culture is performed in aseptic conditions, sometimes contamination occurs, what are the standard anti-fungal and antibacterial antibiotics that should be added to...
10 October 2014 4,249 24 View
Cerium (IV) sulfate is an excellent universal spray reagent especially for plant extracts on TLC. I would like to know the rate of Cerium (IV) sulfate vs. conc H2SO4. What is the best way to...
10 October 2014 6,372 4 View
I am looking for the isolation of onopordopicrin from some Onopordum species, please provide me the RF of silica TLC and mention the used mobile phase.
10 October 2014 3,633 3 View
Bio-transformations of natural and synthetic compounds are performed by using a large range of bacteria and fungi. Can I use a magnetic stirrer for water insoluble compounds; or should I use...
10 October 2014 8,347 7 View
Some drugs are oil soluble, could these oleates be nebulized and taken as aerosols. What are the limitations and risks of these type of formulations.
10 October 2014 9,004 3 View
I am trying to establish a cell culture using the seeds to generate plantlets, but the seeds form a gel layer which prevent the germination. How can I overcome this problem??
09 September 2014 7,772 11 View
I have found some samples of Euphorbia taifensis ( a new species discovered in Saudi Arabia, it was confused with Euphorbia ammak), this plant can exceed 10 meters of high, is it the tallest...
09 September 2014 9,266 10 View
Is it linked to vasoconstriction? What are the consequences?
09 September 2014 7,319 11 View
What are the ethics for the use of human physiological liquids after performing the requested analysis, in other words if some patients perform routine analysis of blood, urine, seminal liquid...
08 August 2014 3,958 5 View
This plant is successfully cultivated in Jordan as ornamental plant, but I am unable to find it as a species in the local or neighboring floras.
08 August 2014 6,170 47 View
This plant is widely cultivated is Saudi Arabia as an ornamental plant, it has a very sweet smell and tolerates the hot, when cut it produces a white latex.
06 June 2014 7,577 33 View
I would like to know the best method for the separation of lectin from plant origin, I will appreciate some review article in matter. 1- what is the best solvent for extraction? 2- what is the...
06 June 2014 4,870 1 View
I tried the extraction of plants in sonicator bath and I got better results of yields. I would like to know if this technique is harmful for the extracted secondary metabolites of the plants and...
05 May 2014 8,352 8 View
Which are the factors which trigger the multidrug resistance in cancer therapy. Why cancer becomes very aggressive for certain patients?
05 May 2014 2,767 9 View
In other words can I reverse compound 3 to compound 1 and 2? Please check the figure.
05 May 2014 5,168 3 View
And what is the prototype drug for each enzyme?
05 May 2014 2,190 4 View
I am interested in the screening of about 70 medicinal plants extracts against Coronavirus. The plants were collected in the Middle East, some of them have an anti-viral effect. I am looking for...
04 April 2014 8,586 2 View
I need some papers which help me to understand the selectivity of amidification and amination reaction, in case of the presence of carboxylic group, ketone function and lactone ring as shown in...
02 February 2014 3,669 6 View
I know a lot of people suffering from rheumatism as a chronic disease; they have started the treatment with non steroidal anti-inflammatory drugs, but the effect does not last for a long time, so...
01 January 2014 8,717 15 View
When I tried to transfer some endangered plants to their original habitat they failed to survive, although they were transferred during the rainy season. Ideas as to why?
01 January 2014 1,796 5 View
Can anyone provide me with the following article as PDF or Scan Copy "Gamal-Eldin, E. 1981: Revision der Gattung Pulicaria (Compositae – Inuleae) für Afrika, Makaronesien und Arabien. –...
01 January 2014 1,459 0 View
What is the behavior of organometallic compounds on TLC? What is the best method for their detection?
01 January 2014 6,002 9 View
What is the role of kynurenine aminotransferase in humans?
12 December 2013 2,338 1 View
Can anyone help me find online courses on the principles and applications of bioinformatics, including in silico drug design and docking?
09 September 2013 6,960 2 View
I am performing a simple bioinformatic study on some diterpenes isolated from a plant, used popularly for the treatment of bone fracture. I am using the program molinspiration.com, some data...
09 September 2013 7,441 0 View
Psoriasis is a very complex and multifactorial skin disease, is it possible to induce an experimental animal model close to human disease?
08 August 2013 1,439 3 View
Hypericin is a photosensitive principle of many Hypericum species, it is a very expensive natural compound, it undergoes a rapid oxidation process in light conditions if I work in normal condition...
07 July 2013 8,963 3 View
Plant histology can help us to identify microscopical characters. Can I predict by section if the plant is an annual, biennial or perennial species? If a perennial plant grows in the first year it...
02 February 2013 571 2 View
Some anti-viral drugs are inactive prior to phosphorylation, but they become active after their phosphorylation within the cells. Which other class of compounds become phosphorylated inside the...
02 February 2013 7,815 2 View
If I know the flora of certain country, and I have found a species which is not included in this flora, what are the steps that I have to follow to discover if this plant is a new species or not?...
01 January 2013 7,497 27 View
Stress is a factor that contributes for the induction of gastric ulcers, could these ulcers develop to gastric cancer? What are the factors involved in this process?
01 January 2013 6,602 18 View
I have some confusion about the exact definition of ecotype and chemotype, is it correct to say: If an aromatic plant continues to produce the main constituents of the essential oil in different...
11 November 2012 5,027 14 View
In the past minimum variety in 2 species gave origin to subspecies, but nowadays when a botanist observes a very small difference between 2 species he/she gives immediately the name of a new...
10 October 2012 9,430 4 View
when I identify unknown plant using analytical flora books some time I face difficult terminology, so i need a pictorial dictionary to understand certain terms.
10 October 2012 4,137 13 View
Some weeds such as "Cynodon dactylon" have the ability to grow in Siberia and in the hot deserts of Arabia. What is the mechanism of adaptation? Do these plants contain adaptation genes? Can these...
10 October 2012 7,470 20 View
TLC, terpenoids, spray reagent, phytochemistry, TLC
10 October 2012 6,620 16 View
During my exploration of the Saudi flora, I have found this Withania sominfera with a strange leaves colour, is it a fungal/bacterial or virus disease, dose this plant deserve a phytochemical...
10 October 2012 2,799 12 View
if you make a search in scopus (plant + anticancer) you will find more than 4000 articles, and if you search (extract + anticancer) you will find more than 3500 articles, but actually the number...
10 October 2012 8,943 11 View
Nanotechnology is an amazing and fascinating emerging new science, I have noticed that some scientist has the ability to adhere to this fantastic science, what is the chance for classic...
10 October 2012 1,230 2 View
Oxidation, oxidase, peroxidase,
09 September 2012 9,831 4 View
what is the simplest method to transform hemoglobin to methemoglobin in simple test tube test? how can I estimate the rate of Fe++ and Fe+++.
09 September 2012 1,524 5 View
