Could Luteinizing hormone (LH) and Follicle stimulating hormone (FSH) be monitored to avoid precocious puberty?

09 September 2018 0 2K Report

Are there LH and FSH antagonists available as drugs that could attenuate the precocious puberty?

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Is there any anti-cancer drug taken by inhalation for the treatment of human lung carcinoma (A549)?

Is there any anti-cancer drug taken by inhalation for the treatment of human lung carcinoma (A549), what are the most suitable characteristic properties for drugs administered by inhalation? which...

05 June 2019 504 3 View

Could microorganisms change the biosynthesis of their usual antibiotic to face new challenges in their growing media?

Microorganism produce their own antibiotic, could they change the type of antibiotic to face some challenges such as stress or the growth of other microorganism in their growing media or to...

01 February 2019 6,021 1 View

What is the solvent of choice that is suitable to suppress the insects?

I found a beetle that emits a bad smell. I would like to extract it in order to isolate possible pheromones. What is the solvent of choice suitable to suppress the insects before homogenizing...

11 December 2018 2,796 0 View

Would you please identify this insect attracted by Tephrosia nubica growing in Saudi Arabia?

I have very limited knowledge in the identification of insects, Would you please identify this insect attracted by Tephrosia nubica growing in Saudi Arabia?

10 November 2018 4,489 3 View

What are the biosynthestic pathways involved in the complete synthesis of cantharidine?

Are the biosynthetic pathways of cantharidine disclosed or not?

10 November 2018 8,459 0 View

What is the best source of correct botanical names of plants-Hypoestes forskaolii is a case?

What is the most official source for plants botanical name, I encountred a problem with the name of plant species called Hypoestes forsskaolii (Vahl ) R.Br. (according to www.theplantlist.org )...

09 October 2018 1,481 3 View

Why Parathyroid Hormone therapy "Teriparatide®" can cause bone cancer?

Parathyroid Hormone is good for osteoporosis in certain circumstances, it is warned that such therapy could cause bone cancer!!! Parathyroid Hormone is good for bone and may cause osteosarcoma,...

09 October 2018 9,863 1 View

Dose MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) exist in cigarettes smoke or tar?

There is a relationship between smoking and Parkinsonism , could MPTP be a degradation product of Nicotine.

07 August 2018 1,511 4 View

Is there any medication approved from FDA for the treatment of multiple sclerosis?

I have read about multiple sclerosis and I was very surprized that no medication is available for this disease! Mayo Clinic stated " There's no cure for multiple sclerosis. However, treatments...

02 March 2018 1,435 11 View

Which factors trigger the glycosidation of flavonoids?

Which factors trigger the glycosidation of flavonoids? is glycosidation a genetical pattern or influenced by exogenic factors?

01 February 2018 6,297 1 View

Is changing the medium during the experiment overestimate the results?

I am experimenting with cancer and non-cancer cells in a 12-well plate for 4 days with a seeding density 1*10^4/well, however, I noticed that the control group growth rate slows down on D3. Should...

07 August 2024 2,283 2 View

Which solvent is better to dissolve with secondary metabolites extracted from fungi?

I work on MCF7 cell cell for anticaner purpose and I wa to do drug preperation the drug ( secondary metabolites extracted from Aspergillus) My question which solvent is better with these secodary...

03 August 2024 4,725 2 View

Can i quantify a nanoparticle encapsulated in cell culture medium by hplc?

Hello, if you made a transwell assay where you incubate the cells with a nanoparticle-encapsulated drug and considering that in the oposite compartment you'll have both the free and encapsulte...

03 August 2024 2,730 1 View

Does exposure to toxins during pregnancy increase early puberty risk?

I am currently researching the impact of environmental toxins on children's health and would greatly appreciate insights from experts in the field. If you are an expert or researcher working on...

02 August 2024 8,361 0 View

How to maintain the drug concentration in cell culture study for long term?

I am working in the filed of long acting drugs with Nano formulation. I want to study the efficacy of my formulation in 2D cell cultures while this required media change on every two days. In such...

24 July 2024 8,696 0 View

How can I determine if a drug binds to a ribosome using a Cryo-EM map?

Hello, I am searching for the binding position of a drug in a ribosome, based on previous work indicating it binds there. The resolution of the ribosome-drug Cryo-EM map is around 2.5 Å. I've been...

19 July 2024 2,155 0 View

How to calculate percentage cumulative drug release?

How to calculate percentage cumulative drug release when, Total volume of dissolution media = 250ml Added formulation was equivalent to 10mg of drug Sample withdrawn = 1ml each time Sink condition...

15 July 2024 4,192 1 View

MTT assay - 6 well plate?

Hi, In the 6 well plate, when I am seeding the cells. Do I add 1ml of complete media to one of the wells for the control at this stage or do I wait unit I am treating the plates to do that? Also...

13 July 2024 9,783 1 View

How to convince decision makers to adjust the legislation to allow opening of drug consumption rooms?

In my country, there is a lot of public outcry in relation to the presence of drug injection and related behaviors in public. Hence at least the bigger cities would probably benefit from the...

08 July 2024 8,903 1 View

Is the use of microcrystalline cellulose MCC 102 in direct compression technology justified, given the low flowability of this excipient?

Hello everyone reading this topic! It is well known that microcrystalline cellulose 102 is recommended for use in direct compression technology, however, like other grades, it has poor flowability...

08 July 2024 2,807 0 View