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Questions related to Cancer Cells
Usually cancer cells have some unique features which are not present in normal cells, for example mutated p53 etc. So i want to know about such unique receptor in HCT-15 cells to which normal...
09 September 2014 6,883 4 View
We know that HL-60, Jurkat and MOLT-4 are p53- or mutated. What about MonoMac-6 and MOLT-3? We are involved in the evaluation of DNA repair (adaptive response)
09 September 2014 318 2 View
Fluorescein encapsulated within polymeric nanoparticles can be visualized uptaken within cancer cells using confocal microscopes and fluorescence microscopes but no significant fluorescence is...
09 September 2014 2,305 5 View
Cancer Biology & Therapy 7:5, 752-759; Monoclonal antibodies target intracellular PRL phosphatases to inhibit cancer metastases in mice. In the above paper, the authors noted that stavation...
09 September 2014 598 1 View
(chirality, chemistry), Could normal cells consume the D aa and then covert it to L aa for building proteins and cell use. On the other hand, could cancer cells consume D aa and not be able to...
09 September 2014 9,673 8 View
I sort cells and culture it but when I culture it CSC population reduces. I sort CD133+CD15+ double positive cancer cells. I check purity of cancer stem cells and it is always more than %90. I...
09 September 2014 3,158 8 View
Is there any transmembrane protein that specifically DOES NOT bind the actin cytoskeleton? I work on mammalian cancer cells, so it would be necessary for me to screen for mammalian proteins. Would...
09 September 2014 2,133 1 View
I use NIH:OVCAR-3 cells for CA125 detection. I now need CA125-negative cells for control comparison. It's been reported that most of the cancer cells do over-express the CA125. Any suggestions in...
08 August 2014 248 4 View
Does it matter if one use media supplemented with 10% FBS and antibiotics to reconstitute cancer cells prior to nude mice xenograft (flank injection)? Will proteins in FBS cause unwanted...
08 August 2014 2,876 6 View
What is the best or common approach by which we can detect co-factors (activators and repressors) of a nuclear receptor (e.g. androgen receptor) in the nucleus of a cancer cell? Any help would...
08 August 2014 7,757 4 View
I am growing cancer cells embedded in matrigel. I would like to split them into a new wells and continue growing them embedded in matrigel. Does anyone have a protocol for passing these cells?...
08 August 2014 3,023 4 View
I recently experienced a case of heterotopic ossification associated with cancer. I want to know immunoprofile of this cancer cells for bone morphogenic proteins (BMPs). Is there anyone who can...
08 August 2014 7,362 2 View
I want to highlight the most important differences between cancer stem cells and more differentiated cancer cells in various tissues whence phenotype , characteristics , behavior of cells , genes...
08 August 2014 6,458 4 View
I need to know the electrical properties of cancer cells.
08 August 2014 5,847 6 View
iam doing reserch on breast cancer cell shape can any one send the images of it, private message me
08 August 2014 6,347 2 View
I treated ovarian cancer cells with as prepared gold nanoparticles and peg modified for 24 hours. Then I collected the cell pellet by trypsinisation and centrifugation. Pellet with as prepared...
08 August 2014 6,442 8 View
Which of the breast cancer cells are less invasive and which ones are the most invasive, do you think? I would like to know more about the mentioned question. Can anyone give advice, document or...
08 August 2014 7,384 17 View
Generally "Cancer cells are acidic in nature". It means that the cells remain in less-oxygenated environment or in some cases, deoxygenated.
08 August 2014 7,013 4 View
The aim of my experiment is to detect the expression of genes in cancer stem cells. I will collect fresh clinical tumor specimen from the hospital and it will take about six hours before...
07 July 2014 595 1 View
What determines the time after which cells can form colonies in the soft agar; why would some cancer cells form colonies within the first week after seeding while others start forming colonies in...
07 July 2014 9,048 2 View
One of our drugs is showing an anticancer effect. It has been found to show G1 phase arrest, apoptosis and microtubule depolymerisation. Besides significant ROS generation detect by ROS. Can...
07 July 2014 6,496 11 View
I am working with cancer cells and assess the effect of different compounds on NFkB pathway and apoptosis. As I observed phosphorylation of p65 upon treatment and a rescue of apoptosis by adding 2...
07 July 2014 6,666 3 View
They are not MHC syngeneic as far as I understand. Could you help us in setting this model up. Is it sufficient to start with a suspension of VX2 cells?
07 July 2014 1,598 0 View
It is well established that basal levels of ROS is higher in cancer. There are two schools of thought: 1. Pro-oxidant could be a potential chemotherapeutic 2. Anti-oxidant could be a potential...
07 July 2014 2,052 24 View