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Questions related to Cancer Cells
Hi Friends I am studying plasmonic photothermal damage effect on cancer (DLD-1) and healthy (Fibroblast) cells. During laser irradiation apoptosis and necrosis indexes of cancer cells exhibited...
02 February 2016 5,157 3 View
Hi all I'm looking for a range of reagents (eg Nocodazole) or methods (eg Mitotic shake off) to block/stall cell lines grown in culture in G2-M phases of the cell cycle. Ideally I'd want to block...
01 January 2016 9,893 2 View
Using stealth liposome is one of the best option to target cancer cells but it also destroys host cells because liposomes are not able to differentiate exactly between cancer cells and host cells....
01 January 2016 5,813 2 View
Hello, Please tell me the best assay to detect the cancerous cells in C3H10T1/2 Cell line. I want to check the effect of radiation on this cell line. Thank you.
01 January 2016 8,578 3 View
When cancer cells are using glutamine as main nutrient, how this means producing huge amount of ATPs? and If cancer cells used glutamine for energy production, is that energy production is going...
01 January 2016 7,471 3 View
There are many debates around the best way of telling the sensitivity of cancer cells to inhibitory drugs. such as GI50 (the dose giving Half inhibition on cell growth compared to non treated...
01 January 2016 4,767 5 View
We have done this experiment twice and in both of them, only the g27 treated cells die after 6 hours.
12 December 2015 8,538 3 View
I am working on evaluating cancerous niches using secretome media and will further with 2D-gel. Do we have any others methods to evaluate secretome other than 2D-gel or LCMS? Beside, is there any...
12 December 2015 1,561 3 View
The few cancer cells that are immortal activate telomerase reverse transcriptase (TERT), a part of the telomerase enzyme that rebuilds telomeres so they avoid a telomere crisis. Normally, TERT is...
12 December 2015 4,388 12 View
Metastasis is an important property of malignant cancer. But it has been found that the pattern of metastasis is different in every type of cancer. Every type of cancer metastasize to...
12 December 2015 9,533 6 View
Could be mitophagy modulation an interesting target in cancer treatment?
12 December 2015 9,220 14 View
Hi Is there any recommendation for how long i need to incubate cancer cells treated with natural product as drug in MTT assay? please explain reasons for the duration you might recommended. Thanks
12 December 2015 6,483 7 View
Hello everyone. I am looking at studying the connection between NF-kB and JAK/STAT3 in normal and cancer cells. I am pretty certain from my research that there is a connection with IL-6. What type...
11 November 2015 5,953 3 View
I read about circulating tumor cells and understood that cellsearch (Janssen) is the only FDA approved method that existing for capturing cancer cells and they are based on antigen-anibody...
11 November 2015 4,816 7 View
Cancer Cell Receptors
11 November 2015 403 9 View
Hello everyone. I am looking at studying the connection between NF-kB and JAK/STAT3 in normal and cancer cells specifically how chronic inflammation leads to development of colorectal cancer. I...
11 November 2015 7,809 3 View
I am try to find a way to differentiated the cancer cells to a point where they are terminally differentiated. They are similar to Neural stem cells which is why I removed all of the growth...
10 October 2015 8,568 2 View
Hello, I just wonder that if SH-SY5Y cell will lose viability or starting to die after it reaches 100% confluent in the culture and culture media is still keeping renewal/replaced. Normally the...
10 October 2015 9,287 2 View
Hi ! I am working on 3D culture of cancer cells forming spheroids in hydrogels for drug discovery and screening. Do you think that these small tumors are the best model for testing anti-cancer drugs?
10 October 2015 7,979 4 View
I have never heard of cancer in the heart, or heart cancer! Is the blood flow there too strong for cancer cells to lodge (to stay there) ????
10 October 2015 8,082 3 View
cancer research, mitochondrial pathway, Warburg effect and metabolic change in cancer cells.
10 October 2015 9,533 1 View
We prepared vesicles from PANC-1 cells
10 October 2015 6,193 3 View
I am building a model of avascular tumour growth and an important question is can cells that are completely surrounded still divide and push out the outer cells. Models I've seen so far consider...
09 September 2015 1,747 3 View
Or is metastasis defined only as the rising of new tumour site for the migrated breast cancer cells?
09 September 2015 1,748 5 View