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Questions related to Cancer Cells
I trying to assess the cytotoxic properties of a substance on breast cancer cells. What are suitable cell lines and how I can calculate objectively the cytotoxic effect?
03 March 2015 5,000 15 View
Unfortunately it rather seems to be a very hard attempt at fitting in the somatic mutation theory which does not work for the majority of cancers by using superlative terms. For the majority of...
03 March 2015 2,589 65 View
Is it by binding membrane receptor or across cell membrane directly? If binding with membrane receptor, how to screen the receptors?
02 February 2015 1,998 5 View
Are there cancer phenotypes which have their reasons not on a genetic level (=mutations in (non)coding DNA or integration of viruses etc.) More precisely, are there any cancer, which has its cause...
02 February 2015 6,300 0 View
I want to inhibit colon cancer growth with siRNA's which target metastatic proteins but some articles have shown that combining with some inhibitors will raise the efficiency of the therapy....
02 February 2015 8,879 3 View
XRF technique to be used in measuring cancer cells in biological samples.
02 February 2015 9,579 6 View
Will Adenoviruses with a mutation in both E1B-55kDa and E1A pRB Binding Domain selectively replicate in and lyse cancerous cells.
01 January 2015 5,837 0 View
I wanted to know how ONYX-015 cells work, and their actual role in killing of cancerous cells.
01 January 2015 6,476 4 View
In normal buffer medium the Co(III) reduced to Co(II) in the presence of some reductant like Iron. Then eject the ligand which coordinate to the cobalt.since cancer cells have more reducing...
01 January 2015 8,952 2 View
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01 January 2015 5,800 0 View
how signal from outside the cell controls cell division,cell growth etc. ? how programmed cell death occurs ? why a normal cell cannot copy itself endlessly ?
01 January 2015 3,965 0 View
We recently completed proof of concept studies with a recombinant fusion protein that activates the TRAIL death signaling pathway in leukemia cells at femtomolar concentrations. The work was...
01 January 2015 8,409 2 View
What is the knowledge of exfoliation of the cancer cells in the abdominal cavity? What type of relation for cancer cells (ie. colon cancer cells, epitelial over cancer cells...) interact with the...
01 January 2015 3,798 3 View
Can anyone tell me what is the actual mechanism involved in targeting a cancer cell form an anticancer drug? How will an anticancer drug target specifically on cancer cells (Which is nothing but a...
01 January 2015 5,789 5 View
Does anybody have a protocol and successfully isolated, grown and expanded cancer cells from leukapheresis of patients with solid tumors such as breast, colon, pancreatic, lung cancer ? Lombardi...
01 January 2015 10,239 1 View
How can I obtain multicellular spheroids from MCF-7 human breast cancer cells.
01 January 2015 9,274 7 View
I have a case of upper extremity sarcoma [High Grade] showing osteoclastic giant cells . IHC- Vimentin +, SMA - +
01 January 2015 2,847 4 View
Why do people use serum, phenol red free media? Are serum and phenol red not good for spheroid formation?
01 January 2015 9,225 3 View
Tumor associated antigens are self antigens, hence how are they different from tumor associated antigens?
01 January 2015 8,601 4 View
If we measure membrane potential of different cancer cells by patch clamp, what are the main considerations, or its similar to normal cells
12 December 2014 3,617 3 View
I know autophagy has a double role in cancer treatment and sometimes it can cause the survival of cell instead of increasing cell death. So, is it possible to be sure that only the killing...
12 December 2014 4,824 8 View
hormone blockade is generally followed by a sharp decrease of PSA to unmeasurable levels. This can mean that the cell population secreting PSA is destroyed or that the cell's ability to secrete...
12 December 2014 6,377 7 View
Is cancer cells (MCF-7) purchased as ready from research institutes be harmful to human body?
12 December 2014 8,524 2 View
I mean are dormant cancer cells the same as quiescent cancer cells? if no, what are the differences?
12 December 2014 6,238 9 View