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Questions related to Peptides
When choosing the receptor model (rigid or flexible) in molecular docking, does it depend on the designed ligands' characteristics or anything else? For instance: + With the ligand A, the protein...
26 June 2024 2,788 0 View
General understanding is that postbiotic particularly those that are heat-treated are stable to heat and their activity remains stable during gastric journey. Wondering if this is true for all...
26 June 2024 3,166 3 View
I am doing research in the United Sates America. So, I will pay in US dollar. Could you please tell me how can i get Zirfon membrane? Thank you.
25 June 2024 7,705 0 View
Hey all what are the ways by which an encapsulated drug inside BSA may escape from its encapsulation. We had synthesised curcumin encapsulated BSA by desolvation method followed by centrifugation...
24 June 2024 8,819 5 View
I've been working with activated sludge samples and have encountered a challenge in identifying certain structures/organisms that appear abundantly within the flocs during optical microscopy...
24 June 2024 9,611 1 View
I follow the protocol in this paper "Computational protein–ligand docking and virtual drug screening with the AutoDock suite" for the "Flexible Docking". Everything is smooth until I write the...
23 June 2024 3,160 2 View
Hello, I have paramterize the residue namely “DOP” into both files of amino acids.rtp and lipids.rtp files of GROMOS96 53a6 force field and charmm27… respectively, although I mentioned the residue...
20 June 2024 7,608 0 View
Can i perform molecular dynamics for ligand only in protein-ligand complex ?
19 June 2024 4,944 4 View
Use of excess amount of BSA is already tested but has not helped us. Addition of 0.01% Tween did not help us either.
18 June 2024 5,547 1 View
In 35 cycle at 94degree C, 54degree C and 72 degree C by mistake in place of 54 degree I did 5.4 degree C and it ran for almost 25 cycle. Can i restart the PCR and what will happen if i did? Thank...
17 June 2024 6,177 3 View
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16 June 2024 6,094 2 View
Arguments 1. Special relativistic principles i.e relativity principle and constancy of speed of light sound more like epistemilogical-philisophical claims rhat cannot be falsified independently...
15 June 2024 7,731 3 View
I wanted to take tem images of my magnetic nanoparticles prepared using iron. It has a magnetic susceptibility below 10 emu/g. Whether this will interfere with the electromagnetic lenses of TEM...
15 June 2024 5,190 4 View
This shape gradually spreads. Even if you install new cells again, it will change like this at some point. Has anyone experienced the same thing as me? I tried using Matrigel again by aliquot it....
13 June 2024 7,303 5 View
I have nearly completed my preparation for the short communication. However, I could use some assistance with the results. Any help would be greatly appreciated.
13 June 2024 4,264 1 View
Dear researchers, I've been working on aqueous plant extract sample, then I autoclaved them in 10 min to sterilize and added some preservatives. However, some of them showed bacterial and fungal...
12 June 2024 1,066 2 View
I need to use a photometer, so i have Cary Agilent and i would like to know what kind of cuvettes and its dimensions and volume i have to order. It's about RNA and DNA samples. Which are you...
12 June 2024 736 1 View
I am currently using API4000 from SCIEX and I have a problem with some unknown contamination. I can see some white powder surrounding the orifice of the curtain plate and some unknown powdery...
11 June 2024 9,632 8 View
I did DLS size measurement with 10 acquisition got average size is 120 nm and STD is 10 while SEM gave me 100 nm and STD is 35 with exactly 1000 NPs. I am sure about the size of DLS should be...
11 June 2024 7,842 5 View
I am working on antimicrobial effect of CBD (Cannabidiol). As it is insoluble in water, I prepared a stock of 500 mg/ml (in DMSO). Now I have two problems: 1- I can not dissolve more than 500 mg...
11 June 2024 9,587 6 View
My interest is to investigate the experiences of parents of pre-primary children towards the implementation of pre-primary education but i am facing challenges the best theory to guide my research
10 June 2024 8,044 0 View
Have you ever seen a small number of cells, 50-100 thousand, after centrifugation as a dry pellet in an Eppendorf tube without a microscope? Are there methods to potentially stain the cells in the...
10 June 2024 6,347 0 View
i am working on self heating membrane preparation. so for crosslinking of membrane, may i use copper chloride, or magnesium chloride or any bi valent cation salt to crosslink it? and which one...
30 May 2024 2,503 0 View
Hi, regarding the use of the method T-Sim/dd-MS2, I cannot see the fragmentations of the ion that I selected with the sim. When I set the method in the inclusion folder I insert my target ion and...
28 May 2024 6,962 0 View