Pharmacology is the branch of medicine and biology concerned with the study of drug action. | Contact experts in Pharmacology to get answers
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Questions related to Pharmacology
I would like to research on the experiences of people with dementia. I know I would like to use interviews, tape recording however I am struggling on finding a methodology. I had thought of IPA...
29 May 2019 7,935 3 View
when two different plant species are examined separately for the same pharmacologic effect in preclinical screening studies, they do produce significant effect for a certain pharmacological...
23 May 2019 9,914 3 View
Why we are boiling the sample at 95 c and for 90 min
23 May 2019 1,425 2 View
I don't know anyone who is expert in this field. I don't have facility to conduct it too. I have done extraction and some characterization on the basis of literature review.
14 May 2019 7,861 2 View
Hi all, We are planning to systemically deliver a synthetic pharmacological compound in rats. When looking for specific dosage and administration protocols, we only found studies with mice....
06 May 2019 3,782 5 View
I am a researcher in medicinal chemistry wanted to work on rheumatoid arthritis. I want to know from where (preferably in India) I can get the pharmacological activity of my compounds??? It's very...
22 January 2019 2,231 8 View
We know that adding a catalyst provides an alternative pathway with lower activation energy. My concern is how would the amount of catalyst change that? For example experimentally if I increase...
11 January 2019 990 5 View
Looking for an answer to this one, also interested in papers regarding 4-HO-DET, 4-HO-MiPT, 4-HO-DiPT, and others. Anything outside of Alexander Shulgin's TIHKAL, and I am specifically looking for...
05 January 2019 4,743 2 View
We face some unsatisfied patients, refractory to standard analgesics even with max doses. It often occurs following major surgeries in both genders but particularly substantial among the...
02 January 2019 9,783 3 View
Pemetrexed (brand name Alimta) is a chemotherapy drug manufactured and marketed by Eli Lilly and Company. Its indications are the treatment of pleural mesothelioma and non-small cell lung cancer....
30 December 2018 8,267 2 View
If comparing formulations of curcumin reported in the literature, which are also available commercially, by their Cmax values, if they have all used different doses, is it scientifically...
11 December 2018 4,714 5 View
what is the most appropriate animal model for humans to study the biological and pharmacological activities of natural substances?
27 November 2018 4,632 3 View
I have a newly synthesized chemical molecule I want to know its pharmacological effect ie is it antibacterial, antinflamatory or anti-carcinogenic? how to know which effect to test? Is there a...
07 September 2018 4,332 4 View
Actually, i am trying to see pharmacological effect of a drug and the drug shows solubility in DMSO. Can it be (5% DMSO) further used as a vehicle for normal control rats? The above...
31 July 2018 1,581 9 View
Would 2 biosimilars, that have separately demonstrated interchangeability with the reference product, through adequate clinical designs (phase III trials with 2 arms, and at least three changes...
24 May 2018 8,771 3 View
Do cell-attached (CA) recordings sufficient for confirmation? I recorded in CA mode with K-gluconate intracellular solution (as after I needed to record firing patterns) without adding any...
30 April 2018 4,561 6 View
Although we can measure serotonin in peripheral blood, it may not reflect its activity in the central nervous system. Pupil dilation may serve as a marker for noradrenaline changes, but I can't...
23 March 2018 9,420 3 View
Hi, I am interested in nucleotide metabolism and performed serial dilution and spotting using ade1 and ade2 knockout yeast strains. it seems like ade1 grows slower than ade2 eventhough they are...
20 February 2018 5,242 2 View
A synthetic compound has a impressive ER-alpha binding affinity, comparable to the clinical standard but feeble anti-proliferation activity on breast cancer cells line. What are the possible...
28 January 2018 4,981 2 View
How it is impact on Pharmacological activity of concern plant?
27 January 2018 6,020 6 View
UPDATE: We made a STATA do-file - see below... Anyone who has the computation of blood pressure percentiles (z-scores) based on the CDC growth charts and the equation given in The Fourth Report...
06 October 2017 5,661 12 View
Hello, anybody knows how could has a demethylase a target gene if is able to demethylate all histone of one type? ex. KDM6B induce RAS_RAF pathway
28 September 2017 361 2 View
I am using HPMC 3 cps with water and currently using 10-15% w/w concentration. What is the important parameter that needs to be controlled to get good granules? My granules always came out as big...
25 July 2017 1,490 10 View
Hi Which one is suitable for treatment in cell cultures: Analytical or pharmaceutical drugs? Which of these drugs has more permeability to the cell?
25 July 2017 6,029 4 View