Pharmacology is the branch of medicine and biology concerned with the study of drug action. | Contact experts in Pharmacology to get answers
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Questions related to Pharmacology
I am in search for any software Developer who can join my Approved Project ADR Project-1, in clinical pharmacy (Adverse drug reaction). The required simulation based software will be designed and...
05 March 2021 4,113 3 View
I want to know, what can physicochemical properties of a transporter protein tell us about it? For example, can we determine the specificity of that protein to a particular type of solute or, can...
01 March 2021 4,690 0 View
Can anyone tell me the impact of setting wrong read length value i.e., 151 instead of 301 during sample-sheet preparation as well as in sequencer (MiSeq) for 16S metagenomic run? Actually during...
25 February 2021 9,600 0 View
A patient was given 300 mg Theophylline taken twice a day for the treatment of her bronchial asthma and has a positive clinical response. She has been compliant in taking her medication however,...
10 February 2021 3,895 3 View
I am looking for a chemical aromatase inhibitor that isn't also biologically active in other ways (or as minimally as possible). Any suggestions? Ideally, should be able to be ingested without...
06 February 2021 8,419 2 View
Microencapsulation of Reservetrol and its water soluble method??
29 December 2020 7,173 2 View
Is there a fluoride home application compliance test, that would tell the use of fluoride in past week or month? Something similar to the glycated hemoglobin test that tells you your average...
29 November 2020 259 5 View
done Thanks
26 November 2020 6,784 1 View
I fabricated the gold layer on the PDMS film. I have to conjugate the surface of the gold layer with cysteamine, however, I heard that cysteamine can damage the gold structure. So, I am confused...
06 November 2020 378 0 View
I would like to pharmacologically increase presynaptic neurotransmitter release in mice CNS in vivo (through the extracellular micro-infusion of a compound). Which strategy would you recommand?...
03 November 2020 5,978 3 View
I have to come up with methods by which an arm could regenerate from the elbow down and I just need some suggestions into pathways that could work in humans to result in limb regeneration so that...
19 October 2020 6,640 3 View
Nitrosamine impurities evaluation, shall we consider API Structure in evaluation. 1. API structure contains Amines, in this case shall i considered API structure ? 2. API Structure contains...
07 October 2020 6,230 2 View
I want to do docking of Poly ICLC with protein. But, unfortunately there is no crystal structure for Poly ICLC or poly IC. Poly ICLC is a complex of Poly IC, poly lysine, and...
25 September 2020 6,402 1 View
I have to carry out certain assays with certain extracts
08 September 2020 3,271 0 View
These phytochemical compounds have been synthesized and are available in large quantities in commercial labs. Why are they not packaged as finished products for their pharmacological effects?
31 August 2020 5,387 3 View
Can anyone recommend an efficient protocol for the extraction of native proteins from cryopreserved, pulverised mouse brain tissue? Ideally, this should also preserve membrane proteins. Thanks in...
31 August 2020 4,937 0 View
Enzymatic methods have been reported for the accurate quantitative determination of tryptophan using Pronase ( Spies. Anal. Chem. 1967, 39, 12, 1412–1416 ) and Papain. Is it possible to use other...
07 August 2020 5,585 4 View
I have just started my postgraduate studies, and I am a beginner who doesn't have knowledge or experience in critique the literature to find the bias or gaps. I want to review articles, but don't...
15 July 2020 5,961 2 View
I want to study the effect of free calcium ion in pharmacological cell based assay. I have around 15mM calcium in my samples. Can anybody suggest how can I chelate with chelating agent (EDTA, EGTA...
28 June 2020 4,033 3 View
My experiment was to determine the xanthine oxidase resistance activity of a sample. I want to determine the IC50 value from % inhibition. Image "data": is the raw data. Image "formula": is the...
23 June 2020 9,598 2 View
I have cloned my gene of interest with N-terminal 1X FLAG tag in a constitutive ectopic vector and transformed in Mycobacterium smegmatis. Now i would like to pull down the interactors of the...
18 June 2020 7,851 1 View
I have been searching the literature for a semi-comprehensive list of histone 1 PTM in humans but I have not been locate a list or partial list of PTM for H1.
09 June 2020 7,546 0 View
Since it is very well known that so many DNA or RNA bioengineered micro-organisms are kept in sophisticated bio labs in the world. Particularly in most developed countries. If these microbes are...
13 May 2020 2,258 0 View
The one-way ANOVA analysis is important to find out whether measured pharmacological effects (the means and medians) observed for three or more drugs are distinct or they are due to a chance....
12 May 2020 4,869 6 View