Pharmacology is the branch of medicine and biology concerned with the study of drug action. | Contact experts in Pharmacology to get answers
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Questions related to Pharmacology
I am working with chemiluminescence substrate in western blot. Some of researchers suggest PBS (phospate buffered-saline)/PBS-Tween 20 for washing the membran after blocking and primary/secondary...
29 August 2016 5,597 8 View
I wish to induce insulin resistance
22 August 2016 7,733 1 View
Dear all: If i discover an antibacterial agent and has been detected its MIC. Which is the right study next? in vivo study and antibacterial mechanism in vitro or inverse?
18 August 2016 6,365 8 View
I'm trying to find the best method to determine H2S concentration in plasma sample from rats. I read about the methylene blue methods and was about to try this when I read about this H2S...
09 August 2016 2,693 3 View
Specifically, epi, norepi, and dopamine
08 August 2016 2,895 3 View
I just read the definition shown: "About Maximum Tolerated DoseThe highest dose of a biologically active agent given during a chronic study that will not reduce longevity from effects other than...
31 July 2016 2,672 3 View
Is it possible to do direct multiple dose BA-BE study of IR test Vs. IR ref. (2-way X over approach). Any regulatory will allow to do direct multiple dose study without single dose study? IR...
21 July 2016 2,883 3 View
No major research in this area.
20 July 2016 2,016 6 View
In which from - (ionic from or anionic form) a drug can better interact with human body? and if so then why?
15 July 2016 4,579 3 View
I have to treat my cells with DHE do i need to wash the cells after treating with the drug and then i have to treat cells with DHE?
12 July 2016 7,210 4 View
Dear Researchers, Instead of bacto casitone what can i use please tell me
11 July 2016 6,322 2 View
I am currently looking for vendors that synthesize TMC207 in a relatively pure form and are willing to ship it to South Africa. I have come across a few on the internet, mostly based in China, but...
23 June 2016 495 1 View
i ready try 100microg/ml conc.solution with further dilution 2-20micro g/mlin phosphte buffer 6.8 and 0.1 M HCl as solvent at wavelength scan 200-400nm.
07 June 2016 9,913 1 View
please answer with complete steps and refrences?
31 May 2016 8,191 3 View
Novel Proton Pump Inhibitor screening, after in-silico studies.
24 May 2016 5,586 1 View
Chloroform is a residual solvent in my product. I prepared the standard solution in dimethyl acetamide as a diluent. i got very poor response of chloroform in GC. I prepared diluent as...
18 May 2016 9,019 1 View
Along with the main question, is it required to keep he animals on fasting for the complete duration of dosing?
16 May 2016 7,119 7 View
I would like to 3D print the 3D reconstruction I obtained from Imaris software, but Cura can only work with STL. How can I convert the format?
11 May 2016 2,306 6 View
I've been working with a Chequerboard method, wich combines one antibiotic and one efflux pump inhibitor. Through that assay, i can determine the FIC index, wich avaliates the interaction between...
09 May 2016 2,540 12 View
What are the minimum number of doses required to calculate ED50 of a sample in animal models? Is there any strict rules for minimum number of doses for ED50 calculation? For example, if there are...
09 May 2016 7,187 7 View
Colon ulcer, inflammatory bowel disease.
08 May 2016 3,566 4 View
I have been told that some anti-viral drugs only enter cells which have been infected by the virus. Apparently, these drugs do not enter cells which have not been infected. I want to know the...
19 April 2016 937 5 View
Both the fluoroquinolones and the beta-lactam antibiotics are bactericidal in action. But they work through different mechanism of action. Fluroquinolones are bacterial nucleic acid inhibitor...
18 April 2016 6,018 3 View
I've read some literature that used saline as a sham injection for the control rats, and some used citrate buffer (vehicle) as the sham injection. Furthermore, the studies that used saline has...
14 April 2016 1,607 12 View