Pharmacology is the branch of medicine and biology concerned with the study of drug action. | Contact experts in Pharmacology to get answers
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Questions related to Pharmacology
i am new to using Imaris and i have a few question regarding thresholding during image processing. When is using the background subtraction in Imaris relevant for the analysis of the image? Do you...
08 December 2018 5,176 2 View
what is the most appropriate animal model for humans to study the biological and pharmacological activities of natural substances?
27 November 2018 4,788 3 View
Cannabidiol is an exogenous phytocannabinoid that has no psychoactive properties similar to Δ9-tetrahydrocannabinol. On the contrary, the antipsychotic and anxiolytic actions of cannabidiol have...
06 November 2018 5,805 2 View
Can case processing (triage, causality, etc.) of published case reports on a particular drug be considered as research project?
03 November 2018 2,010 6 View
How to visualize and identify the formation of lipid droplets .. like wether they are micro lipid droplets or macro lipid droplets..?
02 November 2018 6,153 2 View
When the cytotoxicity of a certain compound measured against both cancer and normal cells, depending on the difference between the growth inhibition of each cells type how can we decide whether...
15 October 2018 8,240 5 View
I have an unknown purified sample which is fractionated through preparative HPLC. Now I need to know the molecular mass of the sample. I have a TQD LCMSMS. Can I measure the molecular mass using...
13 September 2018 6,227 3 View
I have a newly synthesized chemical molecule I want to know its pharmacological effect ie is it antibacterial, antinflamatory or anti-carcinogenic? how to know which effect to test? Is there a...
07 September 2018 4,396 4 View
Hello everyone, I have been on the hunt for an article or just some general advice about FT-IR spectra for human tooth enamel, particularly what is considered an "acceptable" range for C.I....
05 September 2018 3,029 2 View
Does anybody know of a group that has generated a subclone of the 67NR breast cancer line that is resistant to endocrine therapies (i.e., SERMs or SERDs?)
23 August 2018 9,379 0 View
Hi! I am dissociating hippocampus for flow cytometry of glia cells of aged C57BL mice (3, 13 and 23 months old). I would like to use the enzime with the highest mean cellular viability. Some...
21 August 2018 4,490 4 View
I want to create a metabolite pathway with little heatmaps for the abundance of each compound. Is this possible in Vanted? If so, how do I create them?
18 August 2018 1,927 1 View
Actually, i am trying to see pharmacological effect of a drug and the drug shows solubility in DMSO. Can it be (5% DMSO) further used as a vehicle for normal control rats? The above...
31 July 2018 1,671 9 View
We would like want to perform karyotype analysis in our laboratory, could anybody share some simple procedure link for it. We would really appreciate it.
26 July 2018 2,258 0 View
I am trying to analyze whether the expression of gene alters with different receptor status of a poorly characterized gene. Is there any database that we can look into?
30 June 2018 9,010 3 View
Hey guys, I have been working with breast cancer biomarkers HER2, ER, and PR. I have tried to look up charges for those proteins. Just wondering if anyone knows if HER2, ER or PR are positively...
18 June 2018 9,063 3 View
I have worked on invivo toxicity of liver n kidney, now i m shifting towards invitro toxicity of mamallian cancer cell(breast cancer). I just wanted to know how to standralize the protocols i...
01 June 2018 1,136 3 View
Would 2 biosimilars, that have separately demonstrated interchangeability with the reference product, through adequate clinical designs (phase III trials with 2 arms, and at least three changes...
24 May 2018 8,863 3 View
There is a multivitamin capsule I'm working on that ended up being too big, I'm thinking of changing the excipients as a way to make the capsule smaller and more convenient to take. the capsule...
14 May 2018 7,301 8 View
I used Mardia's multivariate normality test in many situations. However, some authors have affirmed it isn't a wholly reliable test.
05 May 2018 6,775 1 View
Do cell-attached (CA) recordings sufficient for confirmation? I recorded in CA mode with K-gluconate intracellular solution (as after I needed to record firing patterns) without adding any...
30 April 2018 4,677 6 View
Pin on disc dry sliding wear testing machine provides the data for wear (height loss). We can measure the mass loss. From both we can find out wear rate of a sample with known density. Which one...
23 April 2018 329 18 View
Ammonium Acetate Method is the widely used method for CEC determination. However, It is not working well with Andosols. Could you please recommend me an optional method? Thanks,
11 April 2018 6,162 0 View
gelucaires are lipids from gattefosse that usually gel at curtain concentrations in water. have any one tried them as excipients in preparation of microemulsions for topical or ophthalmic use?...
29 March 2018 4,193 1 View