Clinical Pharmacology

Clinical Pharmacology and Clinical Therapeutics | Review and cite CLINICAL PHARMACOLOGY protocol, troubleshooting and other methodology information | Contact experts in CLINICAL PHARMACOLOGY to get answers

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Questions related to Clinical Pharmacology

Why magnesium is demanded for diabetics?

Magnesium is element after calcium is badly needed for many diseases he kidneys are important organs that are charged with maintaining a balance of magnesium, according to a study published in...

08 March 2019 9,376 6 View

What should be the size of my sample of COPD patients to be sure that all categories of two different ordinal variables are represented?

This is an observational study on consecutive patients with moderate/severe COPD. Outcomes of interest: quality of life (4 levels) and dyspnea (5 grades).

27 February 2019 2,771 0 View

How can I check a gene set whether it is expressed in a specific cell line or not?

I received a gene set after in silico analysis and I would like to check these genes' expressions in hepatocellular carcinoma cell lines for validation. To choose appropriate cell lines and use...

26 February 2019 6,006 0 View

What are some uses of antipsychotic drugs other than the treatment of schizophrenia?

24 February 2019 5,554 7 View

While modelling the jointed rock in 3DEC, error of "No blocks were Cut with this Joint Set Command" is showing. What can be the reason of error?

Researchers please help me by providing the console command file. TIA

13 February 2019 7,528 3 View

How to assess the effectiveness of a training program on two different performance measures?

Hi I am trying to analyse the effectiveness of strength training program on time trial performance for different sports, running, cycling swimming etc. As the distances, mode and unit of...

10 February 2019 679 5 View

Drug interactions between guanethidine and antihypertensives?

Drug interactions of guanethidine

08 February 2019 5,108 5 View

Cytokines comprises of many substances such as interferon and monokines. What are other substances in embedded in cytokines?

Cytokines are secreted by white blood cells, fibroblasts,endothelial cells, epithelial cells etc. They are soluble hormone-like protein that allow communication between cells and the external...

06 February 2019 5,287 5 View

Is calcium improve breathing?

Calcium is very important for breathing. have found the use of magnesium and or calcium supplements helps my breathing when asleep. Breathing gets controlled by certain mechnisms when you sleep....

06 February 2019 9,426 0 View

What is alternative medicine or food as drug?

Alternative medicine or food as drug is new topic , •tra•ceu•ti•cal (nū-trū-sū’ti-kal), A chemical substance or group of substances that for legal purposes is defined as a nutrient but that is...

06 February 2019 1,056 6 View

What is the load transfer mechanism for paving blocks in pedestrian way?

04 February 2019 4,941 1 View

How to deposit M-O/MgO and Fe-O/MgO interface in MFe2O4?MgO thin film?

Please help me regarding thin film. I am planning to deposit MFe2O4 spinel ferrite on MgO. Is It possible to deposit M-O/MgO interface and Fe-O/Mgo interface by PLD?. If it not possible, any other...

03 February 2019 8,094 0 View

Can we used piracetam injection (for IM/IV use) as an intraperitoneal route in rats for nootropic activity?

I am doing research on learning and memory activity in rats. I have bought piracetam injection which is used for IM and IV route in human but I want to give through IP route in rats. can I do this?

29 January 2019 9,589 2 View

How to calculate static and dynamic metric of ADC?

Iinitially, I was calculating DNL and INL as: 1. Applying ramp input and had taken 2^N samples for N-bit. 2. Giving the sampled input to the ADC and obtained Digital output corresponding to each...

26 January 2019 2,489 1 View

Zero inflated beta regression?

I have vegetation cover data of a species. I am interested to analyse the influence/impacts of predictors on the cover of the species. The cover of species was estimated in percentage (0-100%). I...

25 January 2019 1,516 0 View

How can I deprotect Pbf group without breaking ester bond in the molecule?

I'm trying to deprotect Pbf group from arginine using 1:1 TFA:DCM (v:v). But, the ester bond present in the compound is also getting cleaved. Any suggestions for removing Pbf without affecting...

24 January 2019 3,116 0 View

Does anyone have poundage estimates for rice and cotton from 1770s to 1830s? Pre-ag census, which only goes back to 1840?

Looking for the number of pounds of rice and cotton produced from the 1770's to the 1830's. Any help is appreciated.

22 January 2019 7,333 2 View

Best way to measure accuracy with multiple measurements/data per 1 parameter? ICC, CCC?

My study has 2 components: 1) I have 10 organ and I want to find how accurate surgeons are using 2 seperate measurement techniques for measuring an angle on the organ compared to a gold...

21 January 2019 2,211 2 View

How would you describe these lesions in terms of the color?

Would you describe it as brown? And if so does this mean that purpura preceded this color? And what could be the differential diagnosis of this color?

18 January 2019 9,562 7 View

How to prepare 1M of Oleic acid, Stearic acid and Lauric acid in lab?

I am recently doing my FYP project but i faced prob on preparing the 1M of oleic acid, stearic acid and lauric acid solution. Originally, the lauric acid and stearic acid is come in solid form and...

15 January 2019 886 1 View

Very interesting protocol. Have you had any difficulties with adherence to long term follow up?

We have found over and over again that it is very hard to get people to attend to follow up visits. On the other hand, what dose of ketamine do you usually use? is it in a drip or PRN? Great...

13 January 2019 796 5 View

Structural Equation Modeling with small sample sizes?

I conducted an e-diary study in order to evaluate changes in mood states and life-satisfaction (first-order autoregressive bivariate model). I am interested in within and between person changes. I...

08 January 2019 4,387 3 View

Why is the area under my SYBR Gold fluorescent curve getting smaller with increasing heat?

I am using SYBR Gold to assess the thermal stability of viral capsids. Theoretically, as the capsids are heated, the capsid assembly should disintegrate and the encapsulated genome should be...

07 January 2019 6,256 0 View

I am working on measuring ROS from erythrocytes using H2DCFDA, please what is the best medium to run the experiment?

24 December 2018 3,596 4 View

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