Clinical Pharmacology

Clinical Pharmacology and Clinical Therapeutics | Review and cite CLINICAL PHARMACOLOGY protocol, troubleshooting and other methodology information | Contact experts in CLINICAL PHARMACOLOGY to get answers

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Questions related to Clinical Pharmacology

What is the buffer selection of the hplc analysis for DSP and PA?

My research on " Development and validation of HPLC method for the simultaneous determination of dexamethasone sodium phosphate and prednisolone acetate. I would like to ask which buffer is...

31 October 2020 9,078 0 View

Telepharmacy evolution in this pandemic?

During this pandemic we have changed our complete ways of practicing of normal way, similarly pharmacist are also shifting toward a new concept of telepharmacy. How does it impact the society in...

14 October 2020 8,764 4 View

Are there any electronic databases like PubMed specifically for case reports or case series?

I am interested in identifying all relevant case reports or case series related to a very rare complication of neoplasms. I am currently searching PubMed and CINAHL for this purpose, but I am...

08 October 2020 1,023 4 View

Is there a validated questionnaire/tool to assess patient-level and system-level delays in the management of female patients with breast cancer?

I am trying to assess delays in the management of female patients with breast cancer. I am particularly interested in three delay intervals, but can adapt according to the tools available: 1....

02 October 2020 9,510 6 View

What are the most important websites to monitor in order to find calls for research funds?

Dear colleagues, could you kindly tell me what are the most important association websites to monitor in order to find calls for research funds? My research field is pharmacovigilance and...

10 September 2020 4,758 3 View

Management of the large internal opening in an otherwise uncomplicated cryptoglandular trans-sphincteric fistula-in-ano: which technique is best?

There are a myriad of sphincter saving techniques for trans-sphincteric fistulas. Perhaps a testament to the fact that there is no one size fits all and certainly no “perfect” technique. Clearly...

23 August 2020 6,854 3 View

Hello colleagues, can anyone explain what is the mechanism of action of antimicrobial agents extracted from marine algae on Fungi?

Hello colleagues, can anyone explain what is mechanism of action of antimicrobial agents extracted from marine algae on Fungi?

23 August 2020 874 8 View

How can you measure norepinephrine in frozen adipose tissue?

I would appreciate any suggestions on methodology to measure catecholamines in frozen adipose tissue. Any guidance is appreciated. Best, Molly

20 August 2020 1,446 2 View

Upto how many days can bacteria live without nutrition?

It is a very common established fact that bacterias can withstand long durations of deprived nutrition stages....a recent study diacover a microbe under sea bed which was almost 100 million in...

04 August 2020 5,373 15 View

When there is no melting peak observed in my DSC graph, how do I proceed to calculate the percentage crystallinity?

There is no melting peak observed for my DSC plot. How can I calculate percentage crystallinity of my sample. Sample material is PETG Thanks and regards, Vijayasanakr

02 August 2020 594 4 View

What positive control should I use?

Good afternoon everybody, I currently work on Liver Hepatocellular Carcinoma C3A cells. After Serum starving the cells, I would like to stimulate them with Serum media for 15 minutes and look at...

22 July 2020 5,331 0 View

Is there any alternative of Chlorpyrifos for seedling root dip treatment in Rice ?

I need alternative of Chlorpyrifos for seedling root dip treatment in transplanted Rice.

12 July 2020 9,712 0 View

What are the challenges to finding an effective and consistent solution to the current threats and onslaught of COVID-19 (SARS-CoV-2)?

I think most known volunteers for the trial vaccines have died! Daily declared discovered cases were logged samples in the molicular labs that were just being tested, [slow process and few tests]...

02 July 2020 8,715 9 View

How to draw a ternary phase diagram for a complex elemental composition using FactSage?

I would like to draw a ternary phase diagram (TPD) for the biomass ash I am currently working on. However, the problem is its complex elemental composition. Previously, I have drawn TPDs for 3...

01 July 2020 4,520 7 View

How to use excel to analyze data that has more than 2 variables?

I am working on a project that is looking at antibody levels at different timepoints after administration of different vaccines in transplant patients. The variables that my PI wants me to plot...

29 June 2020 3,978 0 View

Can someone help me with the objectives i can work on with End stage kidney disease patients compared to post transplant ones?

I am working with end stage renal patients together with post transplant ones. one of my objectives is to look at the hla polymorphisms in their loci to see frequencies in their alleles, just to...

21 June 2020 5,777 0 View

Does carbonization at lower temperature produces CNF with better quality than carbonization at higher temperature?

Thermal stabilization and carbonization are essential in obtaining fine electrospun CNF. Some articles report carbonization at quite lower temperature for different composites of the same parent...

19 June 2020 861 6 View

Is it possible to predict olivine FeO content if I have only the MgO content available?

Only MgO content of olivine is available to me. If I want to predict the Fo content only from this data, will it be possible?

14 May 2020 6,013 5 View

Effect of Activation energy in Intensified Reactor ?

Hi, I am working with a microreactor on ester synthesis. I would like to know that is there any effect toward the activation energy of the reaction by using an intensified reactor ? in this case...

09 May 2020 6,443 15 View

How to determine Correlation of phenolic content with antioxidants?

Please guide me in a simple way how to determine correlation of phenolic content with antioxidants please..

14 April 2020 6,449 24 View

Escalating dose regimen with osmotic mini pump?

Hi everyone, I wonder if someone has ever used osmotic mini-pump for an escalating dose regimen. I read that some iPRECIO osmotic mini-pump are programmable and therefore can be used for infusion...

04 April 2020 9,206 3 View

What is the mechanism of action of HCQ+Azi against covid 19 infection?

how H CQ+Azi acts against covid 19?

01 April 2020 4,236 9 View

Effective methods of estimating ligand binding affinity to a protein active site?

Are there any reasonable ways of estimating the binding affinity in like compounds? For example, could I estimate the binding affinity of both tryptamine and 5-Hydroxytryptamine?

22 March 2020 386 3 View

What could be the possible reason for early emergence of Panicles from the Paddy crop ?

This year Rabi -2020(season) all most in all the varieties of the Paddy crop we observed panicle initiation just 30 days after transplanting. Most of the farmers are saying that this year there...

02 March 2020 6,632 0 View

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