It is not even cancer STEM cells only, but malignant clonogenic cells. These may also be post-stem cells that are recruited into a stem-like status.

Also, normal tissue cells - you may call them stem or stem-like cells - particularly from turnover tissues, are able to form colonies and monolayers.

Hi Ibrahim, almost all cells can form separate colonies if you plate them sparsely.

Most transformed cells can do this, but it is more rare with primary cells. 

Hi Ibrahim,

If you plate segregated cells, most cell types (stem, progenitors, CTC, CSC, transformed) can form a colony.

Cheers