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Questions related to Disease Models
How can stem cells repair damaged cells? Could anyone provide papers show the therapeutic potential of stem cells in vitro (on the disease model)?
30 November 2020 9,867 6 View
I am trying to assess spatial memory in MPTP induced Parkinson's disease C57Bl6 mice using a Morris water maze. I wanted to know if there are any specific dimensions to the MWM to be used. Most...
18 November 2020 4,859 3 View
Hello! I performed Morris Water Maze with 5 days acquisition and a sixth-day probe test in rats. Rats had 4 trials per day. Data analysis is confusing. Most of the protocols said that...
12 April 2020 7,792 10 View
I know that C57BL/6 mice are naturally resistant to most types of kidney disease models, such as the adriamycin model, however does anyone know if there are models that they are susceptible to? I...
09 September 2019 9,384 1 View
Are there any self-report questionnaires designed to assess a patient's individual model regarding his (mental) disorder? For example, how a person rates the contribution of biological, social or...
09 September 2019 8,682 1 View
Dear community, I am planing to transplant human cells into a mouse disease model and would require the use of immunosuppressive drugs. Usually I read in publications that people daily i.p....
09 August 2019 2,137 5 View
08 August 2019 629 6 View
Since locust genome sequencing, RNAi and CRISPR is avilable, I tried to model Parkinson's Disease in locust. Injection of rotenone into the head of locusts can cause severe loss of TH positive...
06 June 2019 7,039 3 View
I want to establish some kind of autoimmune diseases model by gene manipulation with AAV or other viral vector.
05 May 2019 6,297 0 View
I want to establish mouse heart disease model by gene manipulation with AAV or other viral vector.
05 May 2019 1,131 0 View
I want to build mouse lung disease models by gene manipulation with AAV or other vector.
05 May 2019 1,397 0 View
i'm gonna count to dendritic spines in a diseased model rat and mice.
01 January 2019 7,609 1 View
During Agarose gel electrophoresis what could be the reason of different intensities of DNA bands of DNA samples extracted from different groups of animal. These groups include control, disease...
12 December 2018 1,010 0 View
Hi, I'm setting the in vitro Alzhimer's disease model. I wonder that SH-SY5Y is dopaminergic neuron, is suitable for AD? AD is related to cholinergic neuron. What is the best cell line in in vitro...
12 December 2018 3,705 1 View
I Have just started studying dynamical systems which consist of ODEs
12 December 2018 1,351 0 View
Hi, I am planning to study cognitive impairment in PD. I will use rotenone as a neurotoxin and will infused it into substantia nigra and ventral tegmental area in SD rats, to induce PD and...
11 November 2018 1,555 3 View
As we all know,vanillin is a kind of crystalline powder.In your article Amyloid-β Deposition and Olfactory Dysfunction in an Alzheimer's Disease Model Olfactory behavior test ,you mentioned that...
11 November 2018 815 1 View
For Alzheimer's disease model behaviour test, I plan to do morris water maze test. Is open field test necessary to confirm the locomotion of the disease mouse model? or the data from morris water...
09 September 2018 2,472 6 View
I am doing research regarding effects of 4 diets on a murine disease model. My finding is diet A has more prominent effect on the disease than diets B, C, D. Is it possible to perform Dunnett's...
09 September 2018 9,963 3 View
infectious diseases are a real news challenge to prevent, any websites or references for that
09 September 2018 9,295 3 View
In any of the disease models
12 August 2018 3,520 2 View
Can a well established cholinergic neurotoxin (AF64A) in animal models be used to induce AD pathology in cell based model of Alzheimer's disease ?
08 August 2018 5,229 3 View
I am trying to evaluate my drug efficacy of clearance of beta amyloid in vivo. but I am not sure whether it is acceptable to inject the beta amyloid intracranially as a AD model?
08 August 2018 3,288 0 View
I am working on the potential of essential oils on an Alzheimer's disease model using neuroblastoma cells SH-SY5Y. How do I dissolve my essential oils into the culture so it would not form a...
28 July 2018 606 1 View