No, It would not be a good choice, since they are not real neurons. You would need cholinergic primary neuron culture to study in-vitro Alzheimer's. In fact in-vitro is not good choice for this disease since cells other than neurons contribute a lot in the Alzheimer's disease pathology. For example glial cells such as astrocytes and inflammatory cells are thought to play a big role in the Alzheimer's disease process. The neurons themselves are not really involved in this disease as the astrocytes, oligodendrocyte and microglia protect the neurons. Therefore, a far better model is in-vivo model of Alzheimer where you can study all cells involved: neurons, astrocytes, oligodendrocytes and microglia.

Hope this helps.

Regards