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Questions related to Bioinformatic Tools
I am checking the synergies between two antifungals and a standard protocol is given by CLSI M26-A document, but i cannot access it. Anyone with a solution or other references kindly share with...
31 December 2020 6,068 1 View
I would like to have access to the pdf "Clinical and Laboratory Standards Institute. 2018. Methods for Dilution Antimicrobial Susceptibility Tests for Bacteria That Grow Aerobically, 11th...
21 December 2020 2,482 4 View
Dear All, I have the data of metabolic pathways in case and control, well there are pathways which are represented several times due to the involvement of reactions in case, well now I would...
10 December 2020 4,751 5 View
I have constructed some polymer structures using Material Studio. But I need LAMMPS input files for the simulation constructed from the Material Studio. Does anyone know how to get lammps input...
09 December 2020 449 1 View
#autodock #virtualscreening Question1: Am I doing this right , means do setting up conda on server works for virtual screening (AUTODOCK)? Question2: How can I modify the script (submit4.py)...
07 December 2020 2,767 3 View
I am interested in the different tools that can be used to create custom databases for targeted sequencing and how to trim the databases based on the amplicon size? Also, should custom databases...
03 December 2020 3,435 3 View
I am searching for new antimicrobial peptides and I don't have many skills in bioinformatics, so I want to know how to use these software packages to identify candidate coding regions within...
02 December 2020 8,607 4 View
I performed an IP protein experiment where I pulled down the protein of interest and attached it to a protein A sepharose 4B bead. I am planning to send this for mass spec at our core facility....
19 November 2020 749 1 View
Dear All We have revealed good results of certain fungal against cercaria of schistsoma. No we are seeking a good online tool, or any other methods to predict the extent of interaction between...
13 November 2020 9,940 1 View
I'm trying to build local gene synteny to identify homologs between different species. To do that, I've been accessing each individual gene of interest, going into gene view in NCBI and...
05 November 2020 9,294 2 View
Hello, I need to draw figure exactly like the ones below? Is there software that can do that for me? Even if not the same design, just the same idea. I can edit their design by myself. Reference:...
27 October 2020 1,571 3 View
I have a set of about 1000 homologous protein sequences with high diversity across various genera and families. What I need is to perform BLAST alignment of each possible sequence pair and obtain...
26 October 2020 1,494 5 View
Looking for tools with proved accuracy to detect ploidy levels in microbial whole-genomes.
15 October 2020 4,516 3 View
Hello, I am working on drawing a phylogenetic tree with samples sharing some somatic mutations. The basic process of my work is similar to this article. Population dynamics of normal human blood...
15 October 2020 8,282 4 View
Hello all, I am trying to choose torsions for an acyl complex, specifically a bond between a carbon and a cysteine sulfur. I can use the addBond command to create the bond, but the 'Choose...
14 October 2020 3,644 0 View
the 2nd protein is of particular interest as it have two forms. their is an experimental hypothesis that its one form can lead to its self degradation in vitro taking it down from bound complex...
06 October 2020 8,503 1 View
How can I add atomic parameters for the ions Europium (Eu3+) and Americium (Am3+)
05 October 2020 2,143 6 View
The mutations in question are variants of the SARS-CoV-2 reference genome (MN908947.3 NCBI reference) – the first isolate from Wuhan (Wuhan-Hu-1).
05 October 2020 1,869 4 View
What does it mean that The same number of decimals after the "." does not mean the same number of significant figures. (41.5821 = 6 significant figures; 0.0010 = 1 significant figure)?
05 October 2020 9,863 3 View
Based on the protocol specified by CLSI that most clinical laboratories follows for disk diffusion testing.
04 October 2020 6,993 3 View
Dear fellows, I am wondering about, how many bioinformatic tools are required to declare a variant as pathogenic and deleterious?
03 October 2020 6,755 3 View
Hello, I would really apreciate if you recommend some free and friendly bionformatic program to determine if a group of genes obtained by microarray are cancer asociated genes? Greetings and...
24 September 2020 7,705 3 View
I want to use data from TCGA available on cbioportal to perform some statistic analysis (e.g: correlation between mRNA of a certain gene and survival data, correlation between the mRNA levels of...
24 September 2020 1,318 4 View
I got LC MS/MS data of two different species of animals, How I can calculate difference in protein concentration,when I compare same protein of both species.
21 September 2020 2,434 3 View