Hello, I would really apreciate if you recommend some free and friendly bionformatic program to determine if a group of genes obtained by microarray are cancer asociated genes? Greetings and thanks in advance.
You can query the gene in String web tool and get the interacting genes in multiple contexts (coexpression, protein protein interaction). If you want only cancer associations you can simply query it in pubmed to get the relevant literature in different cancers. Further, you can check their expression in cancer datasets like TCGA. FOr TCGA I would recommend using GEPIA2 we server/ Oncomine / UALCAN webserver. Just google it and you will get their links.
You can use 'The candidate cancer gene database' here:
http://ccgd-starrlab.oit.umn.edu/search.html
Hi Carlos
you can also use GSEA or DAVID to get pathways related to your list of genes. Typically you could use ingenuity pathway analysis but is a license access.
fred
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