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Questions related to Bioinformatics
I am looking to supply a mid-level plate reader for an entire research service. It should have robust optical capabilities but will not need any time-resolved fluorescence. Are there any brands or...
25 March 2025 4,279 4 View
In the context of my research on a biopolymer with adsorption properties for water treatment applications, I would like to inquire about the number of analyses that would be required to...
17 February 2025 911 3 View
I am confused about the difference between standard, scaled and robust CFI and TLI, especially between scaled and robust, when using 'MLM' as the estimator in CFA. Many thanks in advance if any...
01 July 2024 6,545 5 View
How can prepare Alginate Gelatin Chitosan hydrogel?
06 May 2024 6,400 2 View
Im working on a pectin starch hydrogel, however I can't reach to a specific control protocol where I can make sure the hydrogel matrix is safe for bacterial cells encapsulation and the hydrogel is...
23 April 2024 8,452 1 View
I am aware that random forest is not fitted using maximum likelihood, and there is no obvious likelihood function for it. Is there any way to use AIC for models of this type? Any insights will be...
22 December 2023 6,209 4 View
Good day, I investigate the 3D FDTD and TMM simulations in terms of the grating waveguide. I'm currently setting up the simulation environment and verifying the similarity between the 3D FDTD...
20 December 2023 10,023 3 View
In our ongoing study we aim to assess the fecal microbiome and metabolome in patients in Indian population. For achieving the same we are referring to Franzosa Eric et al's., study entitled "Gut...
12 December 2023 8,882 0 View
Did there exists a dataset which full of Android API sequence(dynamic best)?,I find some, but they are all apk file, if you know please inform me that, thanks!
07 December 2023 3,641 1 View
Hello, I am looking for suggestions for labeling proteins lacking any cysteins and lysines. While, SDS mutation to add a cysteine or lysine are possible options. I am looking for suggestions...
30 November 2023 7,876 1 View
In my thesis I had to analysis multiple correlation. I don't know the main cause of that.
27 November 2023 2,236 3 View
In his very helpful online book on structural equation modeling, Jon Lefcheck writes the following concerning d-separation tests for SEMs: "Once the model is fit, statistical independence is...
21 November 2023 4,616 8 View
Is it the only way to validate the docking protocol in Autodock?
21 November 2023 1,070 2 View
I would like to ask what type of input data do these commands require. I am a little bit lost in the Phylonet manual. Is it possible to construct phylogenetic network in Phylonet using data such...
15 November 2023 2,582 0 View
I have a single cell RNA seq dataset with 9 clusters covering 3 different cell types. I want to get the information on Gene Ontology and Pathways. Should I do a pseudo-bulk analysis or can I go...
14 November 2023 3,556 2 View
I attempted the crosslinking method using glutaraldehyde, which resulted in pellet formation that is challenging to dissolve, possibly due to excessive crosslinking. I'm now seeking an alternative...
27 October 2023 7,156 2 View
I've performed peptide-membrane MD Simulations, is it possible to do PC analysis? If it's possible, how to do it? and after I've made a PCA free energy landscape, How can I find the representative...
02 October 2023 9,987 0 View
primers are short oligonucleotides specifically designed for sequencing and PCR. But if we don't know where to start sequencing for a novel virus's genome then how the primers can be designed? or...
20 September 2023 4,757 3 View
Which software can help me make such graph? Is there any specific command line for creating such graph?
13 September 2023 6,699 0 View
I have inserted my gene of interest into a plasmid, extracted it, and confirmed it through sequencing. Now, I want to create a qPCR standard curve. What dilution should I use for it? (Plasmid...
07 September 2023 5,744 3 View
I am in the process of conducting an electrophoresis and I have a Safer dye at my disposal. However, I am uncertain whether it would be more suitable to combine the Safer dye with the 6X DNA...
31 August 2023 757 3 View
Previously I was getting good DNA concentration for other genes, but for this gene my DNA concentration is very low, also the band was very thin and is and it is always showing non specific...
29 August 2023 8,683 0 View
I encountered the calculations in the research article titled "Theoretical studies on electrochemistry of p-aminophenol ." However, I'm having difficulty comprehending the procedure used to...
14 August 2023 1,804 1 View
In gnomAD website (https://gnomad.broadinstitute.org/), you can write a gene name (such as BRCA1 or P53) in the search box and you can obtain information for a subset of variants as a csv file....
11 July 2023 1,535 6 View