How do I refine a specific region of my protein model so that it perfectly superposes with a template peptide PDB with the same sequence?

I have a protein model and want to replace a 12-amino acids-long region within the center of the model with those of a PDB file containing a 12-amino acids long peptide of the same sequence. This...

02 February 2021 779 2 View

How do we modify displacement boundary conditions while using symmetry?

I'm trying to model a tensile test in ANSYS on a dog bone specimen with one end fixed and a displacement of 5 mm given to the other end. To reduce the computational memory (model has a lot of...

01 January 2020 8,904 5 View

Simulating Raman scattering using comsol?

I want to simulate a very basic Raman scattering experiment using comsol. I shine a light on the material, dipoles oscillate and re-radiate. Can anyone help me with the basic steps involved? I...

31 July 2019 1,036 1 View

Does the peaks at 1767 cm-1 and 1579 cm-1 in IR spectrum indicate the formation of glycolate or glyoxylate in the product?

Hi! I have an IR spectrum of product obtained from CO2 electroreduction in acetonitrile using sacrificial Zn anode. The product formed is normally zinc oxalate. However, at high current densities,...

31 May 2019 7,268 3 View

How to measure water temperature in thin tube with high accuracy?

I am seeking a low cost solution to measure temperature of water in a steel tube of dia 5mm for temperature range 30 - 100 C with an accuracy of 0.1 C. Any suggestions would be appreciated.

03 December 2018 755 4 View

Like Trees of Delhi which gives easy keys for tree identification in Delhi is there any book of similar kind for Uttarakhand State flora ?

15 April 2017 5,515 8 View

How can I studies the reaction path of a complex by Gaussian 09 ?

02 February 2016 1,597 3 View

What would be the advantages and disadvantages of using Dynamic Time slicing concept for scheduling?

Round robin techniques is one of the most popular scheduling algorithms but the problem with that is more context switches, more waiting time. And yes the response time is good in this case. But...

24 August 2013 2,962 2 View

I need to image mesoporous silica nanoparticles that are in ~100 nm size and do high resolution TEM to look at mesopores. what grids should I use?

Need to image mesoporous silica nanoparticles using the TEM. Also, need high resolution TEM images to see the mesoporous structure. Kindly suggest what kind of grids to use. Thanks, Shatadru

02 March 2021 1,787 2 View

Waters 2707 HPLC autosampler problem?

I am using a 2707 waters HPLC device. When I try to inject a sample, it says missing plate or rack. I changed the needle and calibrated its position but I still get the same problem. I even get...

02 March 2021 1,408 1 View

How optimize the Size Exclusion Chromatography?

Hello! I'll do a size exclusion chromatography, but I only have an open column, and I'll perform the peptide extraction from yeast, using buffer lysis (sodium phosphate 50 mM/NaCl 30 mM/DNAse and...

01 March 2021 2,215 2 View

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01 March 2021 3,905 5 View

Can chitosan alone can act as a reducing agent for Cu(0) nanoparticle sythesis?

[Synthesizing Cu nanoparticles without using chemical reductants]

01 March 2021 8,359 1 View

What test should I use to compare two or three means, if data is not normally distributed but sample size is > 30 in each group?

I personally feel this as a most confusing question. As per my understanding, if sample size is > 30, and sample is skewed, we can still use paramteric approach, as it will follow Z...

01 March 2021 1,587 6 View

Is it necessary to report effect size (ES) in statistics of biomedical research given that we already report p values routinely?

Pls share your thoughts

01 March 2021 7,330 4 View

What are the new 2D nanomaterials were used for Silver nanoparticles stabilization?

In the stabilization of AgNPs are vital in current research interest. However, some of the 2D nano-materials like graphene oxide, MoS2, etc... previously used to stabilize it. But still they shown...

01 March 2021 2,207 3 View

What is the state of the drug inside solid lipid nanoparticles (SLNs)?

I am a little confuse with the mechanism of solid lipid nanoparticles (SLNs). The main point of encapsulating drugs into SLNs is because some drugs have low solubility in water. Therefore, SLNs...

01 March 2021 3,703 3 View

How to check the uv-vis absorption of nanoparticle by surface plasmon resonance?

I try to check the uv-vis absorption of Indium nanoparticle. Now I am measuring in solution, can I measure it in the form of a film?

01 March 2021 930 3 View