we tried to use this SPr to check the binding between spike protein and aptamer. we used SA, CM, NTA chips. still, we couldn't produce any data. do anyone here use this machine to check aptamer and protein binding?
I have a protein model and want to replace a 12-amino acids-long region within the center of the model with those of a PDB file containing a 12-amino acids long peptide of the same sequence. This...
02 February 2021 779 2 View
I'm trying to model a tensile test in ANSYS on a dog bone specimen with one end fixed and a displacement of 5 mm given to the other end. To reduce the computational memory (model has a lot of...
01 January 2020 8,904 5 View
I want to simulate a very basic Raman scattering experiment using comsol. I shine a light on the material, dipoles oscillate and re-radiate. Can anyone help me with the basic steps involved? I...
31 July 2019 1,036 1 View
Hi! I have an IR spectrum of product obtained from CO2 electroreduction in acetonitrile using sacrificial Zn anode. The product formed is normally zinc oxalate. However, at high current densities,...
31 May 2019 7,268 3 View
I am seeking a low cost solution to measure temperature of water in a steel tube of dia 5mm for temperature range 30 - 100 C with an accuracy of 0.1 C. Any suggestions would be appreciated.
03 December 2018 755 4 View
15 April 2017 5,515 8 View
02 February 2016 1,597 3 View
Round robin techniques is one of the most popular scheduling algorithms but the problem with that is more context switches, more waiting time. And yes the response time is good in this case. But...
24 August 2013 2,962 2 View
Hi, I have problems with running gel electrophoresis. I have tried agarose gel electrophoresis and native PAGE. I have two proteins, which have molecular weights of ~30kDa and ~180kDa and two...
03 March 2021 4,275 4 View
I am working on a biosensing project on paper substrate, however, it is found that the RNase contamination occurs on the filter paper. Might I ask is there any method to clean the paper surface...
12 February 2021 3,926 3 View
I can find several papers that give me a guide for choosing a suitable aptamer sequence 1. But how to find a property aptamer sequence 2(partially complementary to sequence 1)?
09 February 2021 3,511 1 View
Dear Fellows, now it is the time to push graphene applications further in terms of easy and low cost production surroundings. Thus I recently dived in the materia and I am facing tons of papers,...
02 February 2021 6,284 2 View
I am trying to measure resistance from I-V curve from a chemiresistor/ FET sensor with a keithly sourcemeter. The substrate is soaked/ wet with protein and phosphate buffer only. But the I-V line...
24 January 2021 8,009 3 View
Despite the fact of the tremendous number of research papers in the literature dealing with the usage of aptamers as molecular probes in biosensing, and despite the fact that this technology is...
26 November 2020 1,140 3 View
I would like to know if any carbon allotrope based nanomaterials (such as fullerenes, nanotubes, graphene, reduced graphene, graphene oxide, nanohorns, nanoonions, graphene quantum dots, carbon...
08 November 2020 5,887 3 View
26 October 2020 9,698 5 View
For a range of concentrations of protein, I am getting the I-V (Current-voltage) data from a Keithley sourcemeter. Accordingly, I am getting the resistance as the response of protein-protein...
03 October 2020 8,410 2 View
I am trying to design a boron nitride based biosensor that can sense the abnormality of microbial activities on fish skin. I am very curious that is it possible to have such an aptamer that can...
23 September 2020 6,352 4 View