Genetic Analysis

Genetic analysis can be used generally to describe methods both used in and resulting from the sciences of genetics and molecular biology, or to... | Contact experts in Genetic Analysis to get answers

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Questions related to Genetic Analysis

Hi, does anyone have experiences with the transfection of Primary Nk cells?

I want to do it but I'm a bit concerned about the viability at the end.

13 February 2023 6,959 2 View

Are ACMG rules PS3 and PP3 exclusionary?

Regarding interpretation of sequence variants using ACMG rules. Are ACMG rules PS3 and PP3 exclusionary? In other words, if both PS3 and PP3 rules are fulfilled, can PP3 can be applied? PS3 -...

29 September 2021 7,387 1 View

GENETICS - What would you do if you have 2 million sponsorship?

I'm stuck with ideas what I could do in genetics with this sponsorship. Can anyone give extreme interesting ideas?

14 December 2020 2,696 6 View

May anyone help me to insert binary data into Popgene correctly?

Hello everyone, I am trying to use Popgene 32 software for analysis of binary data for dominant marker of five ISSR primers across five populations and having 38 loci. Unfortunately the program...

23 September 2020 7,543 4 View

How to Download MEGA7: Molecular Evolutionary Genetics Analysis Version 7.0?

I like to download latest version of MEGA7: Molecular Evolutionary Genetics Analysis Version 7.0 but the official link ( http://e.informer.com/megasoftware.net/mega.php ) is not working here....

02 September 2020 1,579 4 View

How can i preserve DNA in tissues for several months to a year or more?

I was planning on researching parthenogenesis in crested geckos using DNA samples from breeders and equipment from my university's lab. However, I graduated in May with a BS in general biology and...

17 June 2020 1,431 4 View

How to make a phylogenetic tree with a specific bacteria in it?

Hello everybody, I´m a student and have no experience with phylogenetic tree. My task is to make a phylogenetic tree of a phylum of bacteria (proteins and rna) according to photosynthesis. There...

08 May 2020 974 3 View

How can I get genetic material from reptile eggs that have not developed (much)?

I am working on a project involving parthenogenesis in crested geckos (Correlophus ciliatus), and I plan on comparing genes- particularly STRs- in samples from the eggs, the potential parents,...

20 April 2020 504 3 View

How can I make a .csv file that could be used in "Genetics" package implemented in R?

Dear all. Hello. I am trying to self learn the usage of r in genetical analysis. Can anyone tell me structure of .csv file which can be read in R from where I can start learning various executions...

11 April 2020 1,335 3 View

Reason for odd increase of relatedness values at 0.5 using TrioML estimator?

Hi all, I have a quirk in relatedness estimates I'm trying to figure out. Any help would be much appreciated! See the TL;DR at the bottom. I have genotype data from 11 microsatellites for...

01 April 2020 9,648 0 View

Goodmorning..when doing genetic analysis of grain yield and yield attributing traits for drought tolerance and yield attributing traits self pollinat?

Goodmorning..when doing genetic analysis of grain yield and yield attributing traits for drought tolerance in self pollinating crops (F2 generation) Vs cross pollinating crops, is it important to...

31 March 2020 1,142 3 View

Protocol: Single-Locus and Multilocus DNA Fingerpriting, Bruford et al. 1992?

Hi everyone! I know this probably isn't the right place for this, but I have exhausted all other options to access this paper. Does anyone has a pdf copy of the chapter "Single-Locus and...

26 March 2020 2,695 5 View

Why Genetic engineering is failed to find treatment for coronavirus?

Highly advanced biotechnology labs cannot find the treatment for coronavirus, which almost at the verge of pandemic. It's killing people smoothly in developed countries.

03 March 2020 829 9 View

Which is the most appropriate graphical method to represent distances between breeds concerning one locus?

I'm studying the polymorphism of a microsatellite related productive performance in 4 goat breeds and I would like to represent the distances between them according to its polymorphism (alleles...

06 February 2020 1,761 3 View

I am in need of a good mechanism for exporting Clinical Variants into an EXCEL table format without resorting to manual entry of each genetic variant?

I am doing research for my thesis which is comparing the genetic variants (genes, SNPS, etc.) of 4 medical conditions. I have identified approximately 7,000-10,000 genetic variants that I would...

02 January 2020 10,074 2 View

Is it possible to estimate the most recent common ancester using o & 1 data? If yes would you please introduce a software?

Dear professors Respectfully, i know that sequences can help us to reveal the most common ancestor in phylogenetic studies. However, in genetic diversity studies using IRAP, SSR, markers etc, i...

14 November 2019 9,437 6 View

Metaheuristic algorithms are time consuming algorithms. Are these algorithms practically applicable to solve real world problems?

I have applied metaheuristic algorithms such as PSO, GA in my research field which is recommender system but what I have found is these algorithms are very time consuming and really not practical,...

14 September 2019 255 10 View

When you are trying to do genetic analysis of a disease, how to decide which genes to look into ? Do you try to follow lit reviews ?

For example, while trying to find about genetic markers of diabetic macular oedema using SNP arrays / exome analysis so how to decide which genes to look into?

02 August 2019 7,541 3 View

How to solve problems arising from choosebank() command in R?

I am using seqinr package in R. But when I am giving the command choosebank() to find out the existing databases or commands like choosebank('swissport") to open any specific database, R is...

16 April 2019 1,740 3 View

How to calculate PIC Polymorphism information content?

05 April 2019 2,747 5 View

How to calculate heterozygosity?

How to calculate heterozygosity ?

05 April 2019 2,439 12 View

What does "Some selected sample(s) do not contain analysis data" error mean in Gene Mapper 5?

Hi all, I am attempting to carry out microsatellite genotyping, using Gene Mapper 5 to analyse data output by the ABI 3500XL Genetic Analyser, but I am encountering an error message I have never...

04 December 2018 3,187 7 View

Type of data file format of SSR loci based genetic analysis of genotypes in Rsoftware?

I have SSR based data file in excel format for 26 genotypes having heterozygous alleles for some of genotypes. I want to go for dendrogram and geentic diversity analysis in R software. Can anyone...

04 November 2018 2,528 3 View

Interaction and subgroup analysis in genetic analysis?

If we conduct interaction analysis and got significant p-value (

01 November 2018 4,361 1 View

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