Genetic Analysis

Genetic analysis can be used generally to describe methods both used in and resulting from the sciences of genetics and molecular biology, or to... | Contact experts in Genetic Analysis to get answers

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Questions related to Genetic Analysis

Which is the most appropriate graphical method to represent distances between breeds concerning one locus?

I'm studying the polymorphism of a microsatellite related productive performance in 4 goat breeds and I would like to represent the distances between them according to its polymorphism (alleles...

06 February 2020 1,776 3 View

I am in need of a good mechanism for exporting Clinical Variants into an EXCEL table format without resorting to manual entry of each genetic variant?

I am doing research for my thesis which is comparing the genetic variants (genes, SNPS, etc.) of 4 medical conditions. I have identified approximately 7,000-10,000 genetic variants that I would...

02 January 2020 10,099 2 View

What Analysis can be done for AFLp marker for plants?

I am using Aflp markers to check the genetic variations and identification of plants, what analysis can done to check the polymorphism, genetic variations etc? I have few softwares genemarker,...

04 December 2019 9,560 2 View

Is it possible to estimate the most recent common ancester using o & 1 data? If yes would you please introduce a software?

Dear professors Respectfully, i know that sequences can help us to reveal the most common ancestor in phylogenetic studies. However, in genetic diversity studies using IRAP, SSR, markers etc, i...

14 November 2019 9,459 6 View

Is there a tool to predict the proportion of r vs K strategist in a 16S rDNA metabarcoding dataset ?

I would like to find a tool (if it exist ...), to predict the porportion of r vs K strategist in samples from a metabarcoding study. For example, the tool I need (R package or equivalent) could...

16 October 2019 3,314 3 View

Metaheuristic algorithms are time consuming algorithms. Are these algorithms practically applicable to solve real world problems?

I have applied metaheuristic algorithms such as PSO, GA in my research field which is recommender system but what I have found is these algorithms are very time consuming and really not practical,...

14 September 2019 279 10 View

Are there any other compounds known to inhibit the ABCB1 ATPase apart from vanadate?

as a way of inhibiting pgp activity by targetting the ATPase

15 August 2019 1,122 3 View

Is it possible to calculate p-values from BA3 BayesAss (Wilson & Rannala, 2003) outputs?

I am conducting a population genetic study on several species of fishes using microsatellite alleles. I have used BayesAss (http://www.rannala.org/software/) to estimate migration percentages to...

09 August 2019 9,202 3 View

When you are trying to do genetic analysis of a disease, how to decide which genes to look into ? Do you try to follow lit reviews ?

For example, while trying to find about genetic markers of diabetic macular oedema using SNP arrays / exome analysis so how to decide which genes to look into?

02 August 2019 7,571 3 View

How to simulate/model real STR data forward in time?

Hi community, I have a dataset of individuals of a species (several populations) genotyped at 9 microsatellites. I would like to ask if (and how) I could simulate that STR data forward in...

17 May 2019 7,284 3 View

Can anyone suggest me which cell membrane marker will work with human skin fibroblast cells?

I used ATPase (ab7671) and ATPase (ab2825) with both mcf7 cells and human skin fibroblast cells, got nice staining in MCF7 cells but these two markers did not work with human skin fibroblast cells.

09 May 2019 267 1 View

How to solve problems arising from choosebank() command in R?

I am using seqinr package in R. But when I am giving the command choosebank() to find out the existing databases or commands like choosebank('swissport") to open any specific database, R is...

16 April 2019 1,780 3 View

How to calculate PIC Polymorphism information content?

05 April 2019 2,777 5 View

How to calculate heterozygosity?

How to calculate heterozygosity ?

05 April 2019 2,487 12 View

How to measure the ratio of protons to electrons in proton pump transport?

What kind of equipments or strategies can I use？

02 March 2019 6,173 0 View

What internal references can be used in western blot of plasma membrane protein,expect Na-K ATPase??

Using pierce kit to extract plasma membrane protein

15 February 2019 2,443 3 View

What should I do to optimize my multiplex PCR protocol for my microsatellite analysis?

I am doing multiplex PCR for microsatellite population genetics study. I have 4 flourescent dyes (FAM, PET, VIC, and NED) with 3 locus pairs each PCR run. Out of my 400+ samples, there are 50+...

13 February 2019 5,380 3 View

Exosome labeling to identify and isolate target cells?

Hi, I would like to identify cells that incorporated specific exosomes. If I use a fluorescent dye to mark exosomes, will it be lost or destroyed in the target cell or will I be able to identify...

13 December 2018 547 3 View

What does "Some selected sample(s) do not contain analysis data" error mean in Gene Mapper 5?

Hi all, I am attempting to carry out microsatellite genotyping, using Gene Mapper 5 to analyse data output by the ABI 3500XL Genetic Analyser, but I am encountering an error message I have never...

04 December 2018 3,206 7 View

How to determine pairwise IBD from high-density microsatellite data?

Hello all, I wish to determine pairwise relatedness and eventually reconstruct pedigrees for a population of dolphins using high-density microsatellites (>2000 loci/individual). However, most...

26 November 2018 6,599 4 View

Type of data file format of SSR loci based genetic analysis of genotypes in Rsoftware?

I have SSR based data file in excel format for 26 genotypes having heterozygous alleles for some of genotypes. I want to go for dendrogram and geentic diversity analysis in R software. Can anyone...

04 November 2018 2,549 3 View

Interaction and subgroup analysis in genetic analysis?

If we conduct interaction analysis and got significant p-value (

01 November 2018 4,384 1 View

Who can help me by add some researches about genetic analysis of isospora belli ?

genetic analysis depending on18 SrRNA of isospora belli .

24 October 2018 8,162 3 View

How Mycobacterium Tuberculosis sputum specimen can be transported across borders (by Flight) for Genetic Analysis in another Country?

In low resource countries, it is difficult to carryout genotyping studies wheere facilities are not available. i am wondering anyone could give me ideas how Mycobacterium Tuberculosis sputum...

12 September 2018 6,614 8 View

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