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Questions related to Drugs
The production of ROS (Reactive Oxygen Species) is toxic to plant cells that deviate or interfere with the normal biochemical pathways. I had targeted quantifying different forms of ROS within...
27 January 2022 4,858 4 View
I want to perform molecular docking between a receptor and a ligand molecule, but the ligand molecule is a linear chain (eg: nonacosane). I have downloaded the structure from PubChem. Is it okay...
26 January 2022 1,310 3 View
Hello everyone, I need how to work with sybyl-X 2.0 software please help me to develop the 3D-QSAR model thank you
26 January 2022 2,662 0 View
I have peptide sequences. I want to add it into a software to predict whether it has anti-microbial potential.
26 January 2022 6,728 3 View
I am working on a development project for ELISA using human sample pools and a newly developed antibody drug. In this assay we use one set of QCs containing ULOQ,HQC, MQC, LQC, LLOQ. And a sets of...
25 January 2022 4,768 2 View
Literature review
25 January 2022 438 4 View
The granules of polypropylene and metal microparticle compound were feed to melt spinning machin. Differential scanning calorimetry (DSC) measurements were carried out to examine the melting...
25 January 2022 5,373 9 View
We are unable to find the control inhibitor of few proteins given below..If anyone knows ,please let me know along with the source you used to find it out(eg. literature,research papers...
23 January 2022 3,526 1 View
Within the small molecule field, there are typically large differences between Drug Substance (DS) and Drug Product (DP). However, given the biological origin of the therapeutic material used for...
20 January 2022 510 4 View
Whether it is feasible to adopt covariate adaptive randomization technique in small-sample (n=40) clinical studies.
19 January 2022 7,625 1 View
Some plants or their products are considered to enhance immunity to diseases. I wish to know the mechanism through which they work.
19 January 2022 4,343 11 View
What is the better method to determinated the mephology of nanoparticles.
17 January 2022 7,902 8 View
Currently a student new to cell culture techniques. Whenever I see reagents in protocols I don't know what most of them mean: Why Dulbecco’s modification of Eagle’s Basal Medium (DMEM) is used...
15 January 2022 6,259 5 View
Which one is better?
13 January 2022 757 6 View
We are trying to capsulate a hydrophobic drug solved in DMSO by chitosan nanoparticle, But immediatley after adding the drug to chitosan solution before applying the TPP, it become cloudy with a...
12 January 2022 8,579 4 View
Hi Everyone I have calculated the effect of a drug on the inactivation of a protein at different temperatures using unpaired experiments. The drug has a significant effect (p
12 January 2022 2,118 3 View
UV visible spectroacopy FTIR spectroscopy Thermogravitimetry (TGA) Prorammable furnace 2500 temp Magnetic hot plate stirrer Vibrating sample magnetometer Electric properties like IV, capacitance,...
11 January 2022 8,017 4 View
What can be the reason for small or not sharp peak in DSC ( differential scanning colorimetry) of a pure drug
09 January 2022 1,281 3 View
We have Vinorelbine tartrate drug with a 10 mg/ml concentration. How can we dilute it and prepare 1 ml of 2 nM (nano molarity) of drug concentration? The molecular weight of the drug is 1079.1.
09 January 2022 6,088 1 View
Hello, I have started doing some bilateral micro-infusions of different drugs in the striatum of mice, using cannula. The goal is to target with the drug as much as possible of the dorsolateral...
08 January 2022 3,817 3 View
I have read many research papers where they had used drugs like erlotinib,gefitinib,sorafenib,dasatinib,methotrexate etc but I am confused about their source.There are tablets available for drugs...
06 January 2022 6,071 5 View
I was wondering about the poorly water soluble drug. How can I administer them to the rats by oral gavage? I have to study the pharmacokinetics of a poor- water soluble drug and I was not able to...
05 January 2022 7,542 3 View
Hello, I ma using microscope for particle size distribution. When I do with API, I saw some particles but when I trying to do with my drug product (ointment),I don't see any particles just...
05 January 2022 10,009 3 View
Dear all, GC analysis revealed the presence of 7.62% methyle salicylate in the final formulation of my ointment, while the initial w/w of MS was 14%. Where it has gone?? If it is because of...
05 January 2022 3,915 7 View