How to convert a methyl group (-CH3) to a carboxyl or amine group (-COOH/NH2)?

Which mechanism(s) or linker are needed to change a methyl group (-CH3) to a carboxyl or amine groups (-COOH/_NH2)?

01 February 2019 7,776 10 View

Looking for reviewers for paper in nanotechnology, nano-medicine,nano drug delivery, nano bio-materials, nano ceramics, and nano related fields????

I am looking for reviewers for my paper submission. Could you please advice me what I am suppose to do? Thank you in advance.

09 October 2015 204 2 View

How can I induce immune suppression in normal laboratory balb/c mice using drugs or other simple methods?

08 September 2015 2,713 9 View

Does anybody know about cell line injections in immunocompetent balb/c mice?

07 August 2015 5,470 10 View

What is the right injection amount for SkBr3 cells in white ICR mice?

04 May 2015 189 8 View

Can someone help me with the methods of HPLC using C18 column to determine bromelain enzyme concentration in juice?

I am looking for the method to determine bromelain enzyme concentration in unknown sample using HPLC C18 column. I would be very thankful and appreciative if anyone can help me with method and...

31 December 2014 6,673 5 View

Which type of functional group will appear in FTIR analysis as peaks after covalent conjugation of enzyme?

11 December 2014 5,686 9 View

What could be the possible reason for a decreasing XRD intensity after citric acid coating?

10 November 2014 4,982 8 View

How can we tell from an M-H curve that the sample is superparamagnetic?

10 November 2014 557 19 View

Does anyone have experience with VSM analysis?

10 November 2014 9,820 15 View

How can I measure MMP-1 protein activity or protein level from liver tissue?

Instead of checking only the mRNA level, I want to check the active protein level of MMP-1 in Liver tissue from mice. How can I do that?

03 March 2021 1,763 2 View

Can we classify HV and LV lines based on line length?

I have dataset which shows the length of power lines. I need to classify the lines based on the line length. Is there a rule to classify the High voltage (HV) and low voltage (LV) lines based on...

03 March 2021 4,116 4 View

No title

02 March 2021 3,060 3 View

How to repeat an operation on an atom selection for multiple times in PyMol?

Hi, I am trying to construct a multi-layer fibril structure from a single layer in PyMol by translating the layer along the fibril axis. For now, I am able to use the Translate command in PyMol...

02 March 2021 4,569 4 View

What analysis to choose with a large neste dataset and clearly skewed or kurtotic distributions?

Hello! I have a dataset of n=3000 nested within 8 countries with approximately 200 or 400 responses in each country. I originally planned to perform multilevel modelling with 4 dependent variables...

02 March 2021 6,865 1 View

Does Napabucasin soluble in dichloromethane and in ethanol?

I need to prepare a solution of Napabucasin (inhibitor of cancer cell stemness) in dichloromethane. The drug is expensive, so maybe somebody already tried to do it. If it is soluble, what is the...

02 March 2021 9,945 3 View

Issues with Permeabilization during Flow Cytometry?

Hello Everyone. Currently I am working to characterize macrophages in the myocardium after ischemia-reperfusion injury in rats. Due to the low total cell number isolated from rat hearts I can...

01 March 2021 3,867 3 View

Could you please recommend some good journal that accept very long revie papers (approximately 6000+ words) in neurosurgery, cancer biology ?

Could you please recommend some good journal that accept very long revie papers (approximately 6000+ words) in neurosurgery, cancer biology ?

01 March 2021 8,087 3 View

Which cell line should we use to perform biological dosimetry experiments?

We are preparing some experiments based on irradiating cells under different conditions in order to evaluate the effects in terms of DNA damage, genetic expression, etc. As our project is...

01 March 2021 3,355 3 View

IHC on mouse liver hepatocytes?

Can anyone help me choose primary antibodies for mouse liver hepatocytes and also in conjunction Cd8 cells. Also Cd3 cells. I want to look at hepatocytes and adjacent immune cells in mice with...

01 March 2021 6,953 1 View