Hello!
I want to perform a hybrid assembly. As the genome is quite large (corresponds to a fungi) I have performed Spades and Canu assemblies (I polished this with MeDuSa and the final result is 67 contigs above the actual reference). I've been searching the best method to merge these too in order to improve the final assembly. I've checked quickmerge but did not worked as I think was not expecting the illumina input. Anyone has a recommendation to improve my result?
Hello,
Maybe you can take a look at Masurca (https://github.com/alekseyzimin/masurca) to perform directly an hybrid assembly ? I work on a Eukaryote as well (but not fungi) and this is what we used when we had Illumina and MinION data.
Thank you Nina! I'm going to try Masurca to see if can improve the final assembly.
- Badges
- Science topic