I need to get the list of microRNAs involving in breast cancer. is there any review paper, database, online tool, etc.?
I am looking for databases that contain microRNA-drug interactions. Any suggestions or recommendations?
09 October 2019 5,273 4 View
I need to study the interaction between some drugs and miRNAs. I was wondering if someone can tell me how can I perform this simulation? Is there any software? or how can I perform this simulation...
05 June 2018 5,816 7 View
I need to construct n*n similarity matrix of n drugs/compounds. I need an online or offline tool to construct this matrix. I have the SMILE of drugs/compounds. any suggestion or recommendation?
11 December 2017 701 2 View
I need PDB format of my desire proteins. I have their sequence. how can I get me question solved?
02 March 2016 2,152 1 View
I need full 3'-UTRs for Bos taurus. who knows where I can get this fasta file? please share any link if is possible.
10 November 2014 5,140 0 View
I'm in need of experimentally validated microRNA negative interaction. I got validated positive interactions from mirtarbase. But I don't know where to get negative ones. Please share if you have...
03 April 2014 662 1 View
For example what's the difference between these 4 microRNAs? hsa-miR-101* hsa-miR-101 hsa-miR-101-3p hsa-miR-101-5p Which pairs (if) are the same? Which pairs are the same in sequence?
04 May 2013 6,852 4 View
What's difference between "hsa-let-7a-5p" & "hsa-let-7a-3p"? What do 5p & 3p refer to?
04 May 2013 10,014 9 View
I need some negative data for running my model. These negative data consists of microRNAs and genes that don't interact with each other. How I get this negative data?
04 May 2013 1,754 4 View
dears: I'm working on chip-seq data. I've downloaded sra format data. to analyze I have to convert them to fastq format and then to SAM file. I made a fastq file but I cant convert it to SAM file?...
11 December 2012 4,215 14 View
I need to prepare a solution of Napabucasin (inhibitor of cancer cell stemness) in dichloromethane. The drug is expensive, so maybe somebody already tried to do it. If it is soluble, what is the...
02 March 2021 9,945 3 View
Could you please recommend some good journal that accept very long revie papers (approximately 6000+ words) in neurosurgery, cancer biology ?
01 March 2021 8,087 3 View
We are preparing some experiments based on irradiating cells under different conditions in order to evaluate the effects in terms of DNA damage, genetic expression, etc. As our project is...
01 March 2021 3,355 3 View
Also when RHAMM binds hyaluronic acid, they get internalized, will RHAMM also be degraded? Or both CD44 and RHAMM will be transferred back to the cell membrane? Asking for breast cancer cell line...
01 March 2021 8,169 2 View
Dear All, mirna primer showing some problem in the melting curve? any idea why? As attached is the melting curve. The forward sequence is obtained from miRBase and reverse primer is universal.
28 February 2021 5,008 4 View
I diluted siRNA and RNAiMAX in opti-MEM and added to the cells which they were in the growth medium. Is it a right way? or should I culture cells in the opti-MEM medium for a while and not in...
26 February 2021 10,041 3 View
In diseased conditions, many genes and gene products are visible in the bloodstream. So my question is whether we can find traces of microRNA which is involved in disease and disorder in blood serum?
24 February 2021 7,064 3 View
Most of the papers have compared different hyperparameters such as layers, initializers, activation function, and optimizer algorithm in the CNN algorithm for detecting network intrusion. This is...
24 February 2021 4,578 4 View
Hi everyone, I am just wondering if we incubated 200 microliter of whole blood with 50 microliter of cancer cells(1bout 5000cells) do you think that cancer would survive for 48 hours?
23 February 2021 3,840 3 View
I have to quantify a mixture of proteins. But I can not quantify its concentration by any protein detection methods as the values fluctuate. Can i quantify the protein concentration by sds page?
22 February 2021 215 2 View