What are the microRNA-drug interaction databases?

I am looking for databases that contain microRNA-drug interactions. Any suggestions or recommendations?

09 October 2019 5,273 4 View

MicroRNAs in Breast cancer?

I need to get the list of microRNAs involving in breast cancer. is there any review paper, database, online tool, etc.?

06 July 2018 4,698 0 View

Software for Drug and miRNA docking simulation?

I need to study the interaction between some drugs and miRNAs. I was wondering if someone can tell me how can I perform this simulation? Is there any software? or how can I perform this simulation...

05 June 2018 5,816 7 View

How to calculate drugs/compounds similarity?

I need to construct n*n similarity matrix of n drugs/compounds. I need an online or offline tool to construct this matrix. I have the SMILE of drugs/compounds. any suggestion or recommendation?

11 December 2017 701 2 View

How can get 3D structure of my desire protein sequence in PDB format??

I need PDB format of my desire proteins. I have their sequence. how can I get me question solved?

02 March 2016 2,152 1 View

Where & How can I get full 3'-UTR sequences for Bos taurus?

I need full 3'-UTRs for Bos taurus. who knows where I can get this fasta file? please share any link if is possible.

10 November 2014 5,140 0 View

What is the difference between microRNAs with star and without star?

For example what's the difference between these 4 microRNAs? hsa-miR-101* hsa-miR-101 hsa-miR-101-3p hsa-miR-101-5p Which pairs (if) are the same? Which pairs are the same in sequence?

04 May 2013 6,852 4 View

What's difference between "hsa-let-7a-5p" & "hsa-let-7a-3p"? What do 5p & 3p refer to?

What's difference between "hsa-let-7a-5p" & "hsa-let-7a-3p"? What do 5p & 3p refer to?

04 May 2013 10,014 9 View

How can I ensure that one microRNA doesn't regulate a specific gene or mRNA?

I need some negative data for running my model. These negative data consists of microRNAs and genes that don't interact with each other. How I get this negative data?

04 May 2013 1,754 4 View

how can I convert Fastq to SAM file?

dears: I'm working on chip-seq data. I've downloaded sra format data. to analyze I have to convert them to fastq format and then to SAM file. I made a fastq file but I cant convert it to SAM file?...

11 December 2012 4,215 14 View

MiRNA qpcr problem?

Dear All, mirna primer showing some problem in the melting curve? any idea why? As attached is the melting curve. The forward sequence is obtained from miRBase and reverse primer is universal.

28 February 2021 5,008 4 View

Can MicroRNA cross the blood brain barrier?

In diseased conditions, many genes and gene products are visible in the bloodstream. So my question is whether we can find traces of microRNA which is involved in disease and disorder in blood serum?

24 February 2021 7,064 3 View

Why CNN algorithm performs well in Network Intrusion Detection based on some recent resources?

Most of the papers have compared different hyperparameters such as layers, initializers, activation function, and optimizer algorithm in the CNN algorithm for detecting network intrusion. This is...

24 February 2021 4,578 4 View

Can i quantify protein concentration in sds page?

I have to quantify a mixture of proteins. But I can not quantify its concentration by any protein detection methods as the values fluctuate. Can i quantify the protein concentration by sds page?

22 February 2021 215 2 View

2D or 3D phased array antennas??

Dear All, I will start my PhD maybe this year regarding phased array antennas. I'm interested in to find more detailed information about 3D phased array antennas and 2D phased array antennas. Then...

21 February 2021 368 3 View

Are exogenous molecules transferred between human cells during doubling ?

Hello RG community, I wonderer whether exogenous molecules (e.g. reporter plasmids, miRNAs or other artificial molecules) are transferred between cultured human cells during their doubling ? So,...

21 February 2021 6,633 3 View

How do I collect online measures in a same-different task?

The same-different task requires to subjects to indicate whether a pair of stimuli seen or heard are the same (say AA or BB) or different (say AB or BA). Researchers often collect offline measures...

20 February 2021 9,226 2 View

MVN, how to conciliate contradictory results from Multivariate normality and Multivariate outliers test?

Dear colleagues, I'm working with Path analyses in lavaan and MVN packages. There are some results that for me are confusing and features from the MVN that I do not know how to set. My dataset is...

18 February 2021 190 3 View

Has anyone encountered any problems with abm good microRNA primers for quantification of mature miRNAs?

I've been trying to quantitate mature microRNAs in 293T cells with and without 'X'. 2ug of total RNA (isolated by Trizol method) is converted to cDNA using All-in one microRNA cDNA synthesis kit...

17 February 2021 8,986 2 View

How to convert isotrophic Deriche filter into anistrophic?

12 February 2021 5,889 6 View