So I am planning to make lipid nanoparticle with 3 different lipids. All I know is the final concentration of lipid is 2 mg/ml and the molar ratio (%) of A:B:C is 60:35:5.
Let's say the molecular weight for A = 550 g/mol, B = 700 g/mol, C = 2800 g/mol
How do I calculate the weight that I need for each components?
Thank you very much for the help
Frederic Lepretre
Hi Najma
let's say that A+B+C=1mole
divide the molecular weight by the respective proportion, you'll have:
(330g of A)+(245g of B)+(140g of C)=1mole of your compound=715g
it lacks some details, as lipids are liquid or solid, and the amount of compound you desire to do, but I think I gave you the key to start...
all the best
fred
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