Helmi Husaini Zainal Fithri FragVLib is a free software application for running similarity searches across databases of ligand-receptor complexes in order to locate binding pockets that are comparable to those of a target receptor.
Sorry late reply, and thanks for suggestion. To answers my objective I used pharmacophore modelling method to search for same features available in the know ligands. I used LigandScout Advance for that purpose.