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Questions related to Rodent Models
I want to test behavior (Elevated Plus Maze, Tail Suspension Test and Morris water Maze) in mice after social isolation. Which strain do you recommend for my situaition? Are there any significant...
05 May 2015 8,441 7 View
Extracting blood from rats that age has been proven to be difficult for many of our lab members.
11 April 2015 519 3 View
04 April 2015 7,010 3 View
How long does it typically take until a control rat will begin exploring the open arms of the elevated maze?
04 April 2015 7,427 6 View
Hi all, I'd like to record locomotion and rearing in rats in open field cages. I am thinking to use a setup with two rings of photo beams and I got quotes from three different companies. Could...
04 April 2015 3,316 10 View
can anybody suggest some behavioural studies that i can do in syrian hamsters?i have control and prion infected groups?any memory analysis tests?
04 April 2015 9,602 2 View
We would like to evaluate small molecule compound(s), where exact mechanism-of-action is not clear at the moment. We are conducting in vitro studies right now and would like to extend these...
15 March 2015 4,815 3 View
Did the moving of rat on the edges of the closed arm of the elevated plus maze measured as close or open time? in our observation, some rats moved on the edges of the closed arm of the elevated...
03 March 2015 2,579 7 View
This to enable an explanation to the cause of the death whether it is the administered substance.
03 March 2015 6,114 3 View
03 March 2015 6,109 3 View
I had a point mutant mouse generated from a company. The mouse has the correct sequence and is a HET. When I set up breeding pairs, only HET and WT pups are born. No homozygous "mutant' pups...
02 February 2015 5,714 7 View
We are looking for buying a software to analyze different kinds of behavioral task in mice and rats. Up to now, we have used ethovision, but we have heard about any-maze as an another choice. It...
01 January 2015 1,596 2 View
If I have drug A used for human 45 mcg/day, how much do I have to use for a rat weighing 250g.
01 January 2015 460 2 View
We want to induce hypocholestrolemia in rats to compare hypercholestrolemic rat testis?
31 December 2014 7,169 3 View
12 December 2014 5,574 4 View
In regard to the preparation of acute brain slices, animals are anaesthetised, confirmed areflexia, and then decapitated. In my case, if I am going to study the hippocampus, then only the regions...
12 December 2014 1,567 0 View
I am faced with problem to use the same or close to the same actual concentrations of drugs in behavioral tests, as in electrophysiological experiments. Does anybody know the ratio between the...
12 December 2014 9,372 1 View
Any one who could suggest on "why rats are used in OGTT but mice for hypoglycemic test in most of animal based studies to investigate the antidiabetic potentials of medicinal plants?"
12 December 2014 4,210 3 View
I am looking at the effects of a compound on blood-brain barrier integrity. Preliminary results indicate that the compound improves tight junction expression in aged mice. I am looking for a way...
21 November 2014 8,045 8 View
11 November 2014 2,053 9 View
We are interested in using this task in our experiments with Wistar rats. What is the best protocol?
11 November 2014 3,710 2 View
Hi, anyone knows which animals are suited for a aortic formation study (cardiovascular disease) - rat or rabbits? Rat has a tiny aorta which is difficult to be sampled and cut compared to rabbit.
15 October 2014 7,179 7 View
10 October 2014 6,285 8 View
....by analogy to Gpp(NH)p (but which works only in vitro) Our aim would be to use this compound In vivo (rodent models), i.e by iv injection or brain local perfusion/injection.
09 September 2014 9,409 2 View