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Questions related to Rodent Models
Several months ago we observed some strange changes around eyes of several individual Siberian hamsters (Phodopus sungorus) in our colony (outbred). I attach pictures. It looks like an...
18 July 2020 10,188 3 View
I am not sure I understand the mechanism to detect behavioural signs for tinnitus in rodent models.
07 July 2019 3,829 5 View
Lamina Cribrosa is a tough membrane (actually a continuum of the sclera at the site of exit of optic nerve from the eye). Sclera is perforated here so that the nerve fibers assembling into the...
23 May 2018 3,650 7 View
05 May 2018 6,658 8 View
There are other methods of sleep deprivation that includes some of the automated setups validated and published couple of years back. But I am looking for the wet cage method of restricting sleep....
02 February 2018 2,189 0 View
Looking to use a T2DM rodent model.
12 December 2017 4,983 3 View
Hi! I would like to calculate the FCR for a diet-induced obesity experiment in rats. Since I have many nutrients/groups, I am calculating the food intake (FI) in kcal, not in grams of food. Has...
11 November 2017 1,892 4 View
10 November 2017 5,518 5 View
In my laboratory we only have the conditions to use small rodents, rats or mice (or cell lines). In your opinion, what is the best model for studying the long-term effects of gestational diabetes...
10 October 2017 4,072 6 View
Seven decades ago, the chance "discovery" of cortical spreading depression unleashed a storm of excitement amongst neuro-scientists, and, a spurt in animal experiments to replicate the findings...
08 August 2017 9,772 0 View
I am getting very faint bands and cannot seem to increase the signal. I have tried increasing the amount of protein per well, increasing the primary antibody concentration, 0.45 and 0.2 um...
04 April 2017 4,414 5 View
I have an older version of grip strength meter(GSM) UGo basile cat # 47105-001 can any one tell me how i can use it?? Actually its user mannual have lost and i cann't find user mannual of this on...
03 March 2017 7,543 0 View
I'd know the optimum period of activity of this specie, is at night?
11 November 2016 6,214 2 View
04 November 2016 8,751 2 View
I currently have the NPC1-Flag knock in line (Sugimoto et al PNAS 2001 / Sharom et al JBC 2008) and have been trying to locate the parental cells with no success. I cannot use the common CHO-K1...
10 October 2016 9,731 2 View
l recently received feedback from my reviewer; saying that my rodent model of drug administration is not chronic. we administered twice daily for 28 days. so the question would be what is...
07 July 2016 7,197 3 View
Hi all, I have a question about the von Frey assay (or really, any nociceptive assay where multiple animals are in close spatial proximity). I am using both male and female mice now, rather than...
05 May 2016 8,490 7 View
I found nearly all papers use male rats.
05 May 2016 6,450 2 View
I am going to execute a protocol of corticosterone administration in rats for which I'll have to prepare a solution of corticosterone in a vehicle of saline (0,9%) with Tween 80 (20% v7v). The...
04 April 2016 7,496 2 View
The research focus is Mastomys natalensis, I intended to characterize the Mastomys by morphometry and chromosomal number verification. It will be very helpful to have a easy-to-use protocol from...
04 April 2016 4,597 0 View
01 April 2016 1,017 2 View
Dear all, I am currently working with ghrelin (a gut peptide) and I would like to check if the peptide crosses the blood brain barrier and if it is possible to find out in which areas it reaches....
10 March 2016 7,150 5 View
03 March 2016 754 6 View
wel...l is there any easy way through which i can statistically analyze the videos that i made for memory tests specially i wanna check locomotion and rearing activity with a the central novel...
03 March 2016 8,618 5 View