noncoding RNA like microRNA and SiRNA,can have main role in some disease like cancer,they can supress or active expression of some gene,they attach specific to RNA and inhibit expression of it with degrdation RNA.for example microrna attach to RNA of tumor supresor gene and inhibition of tranlation of this RNA(it cause cell cycle don't stop in checkpoit )

we can use this microRNA for therapy,with specific degrade some RNA,inhibit expression of them.it shoud does very specific,witch gene we want to inhibit,so design miRNA for it's RNA ,and supress it's expression.good luck

Thank you.

Do you have a paper which gives introduction about the non coding RNA exclusively.

Here is an interesting review on the subject. Are you interested in neuroscience, cardiology .... as this changes the type of review that you might find interesting/relevant. B :-)