Do you know journals for free publication cost?

Dear all, i am looking for a list or suggestions for biomdical jurnals that can publish for free or waiver publication cost for authors from low income countries. I know about the BMCs but I need...

04 May 2019 8,833 4 View

How to use NEBcutter?

Hello everyone, I would like to use RFLP to detect specific SNP. I would like to selelect specific enzyme that cuts in certain nucleaotide using NEBcutter but I do not know if I did well using...

10 November 2018 5,629 0 View

What are the parameter of the bioinformatic tools?

Dear all, Now a days there are too many bioinformatic tools and sftwares freely available on the net like SIFT and Polyphen. These tools are able to predict the effect of specific varaiant on...

09 October 2018 591 2 View

Is there anyone familiar with CYP21A2 gene?

Hello all, I am using panel sequancing and I found a homozygous mutstion in cyp21A2 gene. I did sanger but couldnt find this mutation. I think there is a possibility that I sequanced pseudogene....

09 October 2018 2,831 0 View

What are the bioinfromatic tools that can predict deletions and insertions?

Hello everyone, I am working on some SNPs and mutations and I would like to have good prediction tools. It is easy to find bioinformatic tools for SNPs prediction but I couldn't find prediction...

06 July 2018 3,252 0 View

Can anyone recommend a good booksand programs for biostatistics?

Hello everyone, can you please recommend good books for biostatistics for both beginner level and a little advanced level? I also would like to have or advice for a good satistical progams that...

03 April 2018 222 7 View

Why project HOPE couldnt find the amino acid change?

Hello everyone, we extracted SNPs from dbSNP then we retrived the protien sequance from Uniprot. Then we submitted the amino acids changes corresponding to the protien change to proiect HOPE...

02 March 2018 1,419 1 View

Can any one help me with protien stability prediction tool?

Hello every one, I am looking for a bioinformatic tool for protien stability prediction. Can you please suggest for me? or provide me with links? Thank you

02 March 2018 5,562 5 View

Why Alleles in the same SNP changes?

I would like to know the wild type and mutant type allele of rs1344706 but some time I find it A/C and some times I find it G/T. Is this has anything to do with NCBI assay ID? Will a SNP has the...

02 March 2018 1,675 5 View

What is the molecular weight of hpv e6 protien and scrible?

05 June 2017 2,804 3 View

How to repeat an operation on an atom selection for multiple times in PyMol?

Hi, I am trying to construct a multi-layer fibril structure from a single layer in PyMol by translating the layer along the fibril axis. For now, I am able to use the Translate command in PyMol...

02 March 2021 4,569 4 View

What analysis to choose with a large neste dataset and clearly skewed or kurtotic distributions?

Hello! I have a dataset of n=3000 nested within 8 countries with approximately 200 or 400 responses in each country. I originally planned to perform multilevel modelling with 4 dependent variables...

02 March 2021 6,865 1 View

How to plot the probability paper of Gumbel distribution using R programing?

In R-studio, there are many commands of Gumbel package. Arguments are also different. I`m asking about the alpha parameter of the Copula which must be greater than 1. If this is the one used to...

25 February 2021 5,229 3 View

Alginate and silk fibroin hydrogels toxic to cells?

Hello, I asm currently working with alginate and silk fibroin hydrogels. I prepared a blend of alginate and aqueous silk fibroin (straight from dialysis) and resorted to ionic crosslinking to...

23 February 2021 8,249 2 View

Are there methods for automatically mapping floodplains, fans and terraces?

I want to map these river geoforms with as little subjectivity as possible. I have a high resolution DEM generated by drone data.

22 February 2021 7,800 3 View

Are there any databases for gene co-expression or expression pattern clustering?

I am currently working on gene clustering based on co-expression pattern in mouse brain. The problem is I do not have some solid way to test my result. Are there any suggestions for databases...

22 February 2021 4,374 3 View

Do I need to introduce HFD to ob/ob mice to obtain a T2DM model?

I am planning to work on T2 diabetic animals and check the efficacy of probiotics. My initial plan is to fed B6 animals with HFD for a while. But now, I have the chance to work on ob/ob mice. My...

18 February 2021 6,896 3 View

What are the options for global scale hydrology DEM?

Hello, I am working on a global scale hydrology GIS project delineating global watersheds and doing some data analysis. I have in the past used hydro1K from the USGS that cover the entire world....

18 February 2021 5,109 5 View

Can I use a categorical covariate in a Generalized Linear Model in SPSS v.26?

Hello everyone, hope you are well. I am planning to use a Generalized Linear Model in SPSS. I would like to add gender to the model as a covariate, however from what I have read, only continuous...

14 February 2021 8,937 4 View

Mixed ANOVA or Multilevel modeling?

Hi everyone, I'm having some questions about choosing the right test for my experiment and I hope I can find help here! Here are the settings of the experiment: 1. participants are randomly...

14 February 2021 1,028 4 View