Input your protein sequence on ProtParam, which will return a stability index of the protein. We have purified proteins with high instability index, so results are not necessarily true.
1. François Ancien, Fabrizio Pucci, Maxime Godfroid & Marianne Rooman.Prediction and interpretation of deleterious coding variants in terms of protein structural stability. Scientific Reports; 8,: 4480 (2018).
2. Seifi M, Walter MA (2018) Accurate prediction of functional, structural, and stability changes in PITX2 mutations using in silico bioinformatics algorithms. PLoS ONE 13(4): e0195971. https://doi.org/10.1371/journal.pone.0195971
3. Computational tools help improve protein stability but with a solubility tradeoff Aron .Broom, Zachary Jacobi, Kyle Trainor and Elizabeth M Meiering; JBC Papers in Press. Published on July 14, 2017
4. Geetha Thiagarajan, Andrew Semple, Jose K. James, Jason K. Cheung & Mohammed Shameem.A comparison of biophysical characterization techniques in predicting monoclonal antibody stability; Journal mAbs; 8, ();61088-109 2016