I suggest for the following reading

Article High Throughput Sequencing of Extracellular RNA from Human Plasma

Thanks for the paper. From the above paper:

Despite the large variation in the total number of miRNA reads, all three samples yielded more than 346 mature miRNA with PK-in-GITC sample yielding the most diverse result (n = 428). Overall we identified reads mapping to 593 mature miRNA across samples with detectable counts (count>0, S1 Table), but only 210 out of 593 miRNA were shared among them with modest level of correlation (r>0.43, Spearman Correlation, Fig 2), suggesting strong miRNA profile variability as a result of different PK treatment. If only miRNA with >10 reads were considered, the number reduced to 97 shared and 198 total mature miRNA

Thank u for recommending my answer@

• Yehya A. Salih
• Jia-Wang Wang