How many genotypes are there in HCV virus? WHO web says 11 whereas NCBI web says 6!
There are 6 main HCV genotypes but within each genotype it is possible to distinguish various distinct HCV subtypes (e.g. Genotype 2a, 2b, 2c and 2d). If you consider all these subtypes as Genotypes then there can be even more than 11 genotypes.
Thank you Sir! The different information given on different web pages confused me.
Sorry for get the topic back but just to complement Pedro's answer there is a seventh genotype described in a AASLD meeting and then confirmed by cell culture models with celular receptors studies. The abstract is in the page 623A of the link and the publication is on the link.
http://onlinelibrary.wiley.com/doi/10.1002/hep.22019/pdf
The publication
Article Development and Characterization of Hepatitis C Virus Genoty...
According to the World Health Organization "HCV is classified into eleven major genotypes (designated 1-11) and many subtypes (designated a, b, c, etc.). Genotypes 1-3 have a worldwide distribution. Types 1a and 1b are the most common, accounting for about 60% of global infections. They predominate in Northern Europe and North America, and in Southern and Eastern Europe and Japan, respectively. Type 2 is less frequently represented than type 1. Type 3 is endemic in south-east Asia and is variably distributed in different countries. Genotype 4 is principally found in the Middle East, Egypt, and central Africa. Type 5 is almost exclusively found in South Africa, and genotypes 6-11 are distributed in Asia". (Genotype 7 is found in Vietnam).
I think, we should go with WHO data. Because, NCBI mentions only those whose sequences have been revealed till now.
Website for your information. http://hcv.lanl.gov/content/index http://s2as02.genes.nig.ac.jp/ http://euhcvdb.ibcp.fr/euHCVdb/
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