14 Questions 97 Answers 0 Followers
Questions related from Pedro A Reche
I read a while ago that tetatus and diphtheria toxoids only represent about 50% of proteins in vaccines but I cannot find the original reference. Please, if someone knows about it share the info.
07 February 2023 1,569 4 View
I have identified a potential CD4 T cell epitope in a human proteins that is similar to that found in a viral antigen. Now I'd like that prove T cell cross-reactivity between the two antigens. Any...
03 October 2017 1,072 1 View
I have obtained distance matrices whose coefficient are related to binding specificity of different molecules. The distance matrices are suitable for the Phylip package and I can get nice trees....
26 November 2015 2,621 3 View
Multiparous women often exhibit atibodies against foetal HLA antigens inherited from the father. These anti-HLA antibodies belong to the IgG class and should cross the placenta freely, yet, as...
02 November 2015 1,353 11 View
I am using blast+ tools on the command line with local databases. I would like to do a blast against nr limiting the search to a given taxon, just as one can do in the blast web. Is that...
09 April 2015 2,568 5 View
I am getting negative branches with the Neighbor-joining method, which I set to zero. However, I've read that I should transfer negative distances somewhere else and I do not know how. Does...
23 February 2015 3,954 4 View
Immunologists often prime and stimulate T cells using antigen-loaded APC in vitro and I wonder if you also get memory T cells.
03 April 2014 2,292 8 View
I am trying to align a sequence to a multiple sequence alignment obtained from an 3D-structural alignment (superimposed 3D structures). The sequence is related to the sequences in the multiple...
30 May 2013 8,511 15 View
We need synthetic peptides for Elispot assays and we wonder from which company to get them. We have found that ChinaPeptides offer peptide synthesis at very competitive prices. However, we have...
03 April 2013 6,517 3 View
ClustalX has an option to obtain bootstrap neighbor joining trees from an alignment. However, the trees differ considerably from those one can get using bootstrapping with the phylip package...
17 January 2013 2,674 13 View
I understand Th1/Th2 T cell polarization occurs in secondary lymphoid organs (e.g. lymphatic nodules), where T cells recognized the antigens in the presence of different signals that condition...
07 September 2012 8,297 17 View
I would like know what controls protein expression levels in HCV. Any help/reference will be appreciated.
19 June 2012 7,287 3 View
FcgRII-I is an inhibitory receptor expressed in both naive and memory B cells. However, in naive B cells, this receptor prevent the response against antigens for which there are preformed...
27 April 2012 4,633 3 View
We are having here a discussion over a scientific topic and I thought I can get here the help to settle it. The diversity of the immunoglobulins is generated by stochastic rearrangement of...
25 April 2012 8,386 12 View
