35 Questions 50 Answers 0 Followers
Questions related from Vipul Patel
Therapeutic compounds with short half lives are excellent candidates for sustained release preparations. Is it true?
20 December 2017 5,272 1 View
Stent Can be coated with drug embedded in a surface polymer. Drug-eluting coronary stents can help prevent plaque buildup, promote good blood flow to your heart, and relieve chest pain. They may...
22 November 2017 1,916 3 View
Insulin Jet delivers insulin subcutaneously without using needle. It is achieved by pressurizing the liquid through a small orifice which creates high speed jet that can penetrate the skin and...
22 November 2017 130 1 View
In Last GST Council meet in November 2017, GST rate for cosmetics products reduce from 28% to 18%. Will it boost pharma buisness?
11 November 2017 5,272 0 View
From, One newspaper article and also in one magazine (http://sharonglasgow.com/2016/04/no-disease-can-exist-in-an-alkaline-environment/), It is concluded that No disease exist in alkaline state of...
10 November 2017 5,411 1 View
Many Private organization also provide ISO certification. Which are accrediated Board and Bodies that provides ISO certification across globe?
09 November 2017 812 3 View
In one of formulation, I need to improve viscosity of Acetone ans IPA.How to increase viscosity of solvents like Acetone and IPA?
07 November 2017 2,474 2 View
What is best therapeutic treatment for chickungunia? Which herbal source having best effect in treatment?
07 November 2017 6,143 4 View
What are impacts in pharmaceutical API manufacturing industry and finished formulation?
06 November 2017 9,038 3 View
Scientists have raised serious concerns about the widespread use of one of the world's most common painkillers after studies showing that codeine may be unsafe, ineffective and potentially...
06 November 2017 8,629 1 View
What is the acceptance criterion for accuracy when validating a dissolution method for a modified- release dosage form?
05 August 2017 7,891 1 View
In one of the scientific paper on dissolution testing where the dissolution test was performed at 25 °C and at 47 °C. What could be the rationale for using these temperatures instead of 37 °C?
05 August 2017 5,753 4 View
The dissolution test in a particular USP monograph uses pooled sampling. We would like to do a dissolution profile comparison using f2 for this product. Can we use the pooled sample results for...
05 August 2017 3,423 2 View
For unknown drugs, I want to find their BCS class.
27 July 2017 9,232 7 View
In dissolution study of buccal tablets, How to select dissolution fluid and their volume if drug's formulation is not official in pharmacopoeia.
27 July 2017 4,766 2 View
In dissolution study of gastro retentive tablet , How to select dissolution fluid and their volume if drug's formulation is not official in pharmacopoeia.
27 July 2017 2,150 3 View
In dissolution study of colon targeted tablet , How to select dissolution fluid and their volume if drug's formulation is not official in pharmacopoeia.
27 July 2017 9,504 3 View
In dissolution study of sublingual tablets, How to select dissolution fluid and their volume if drug's formulation is not official in pharmacopoeia.
27 July 2017 5,076 2 View
In USP General Chapter Dissolution under Procedure, Apparatus 1 and Apparatus 2, Immediate release dosage forms, it says to verify the temperature of the mixture under test in the...
18 July 2017 6,900 3 View
The dissolution test results for a particular product have a high variability and are very high. What is the upper limit for the amount of drug released in dissolution testing?
18 July 2017 4,479 7 View
Our equipment enables sampling through the paddle shaft, in the middle of the vessel, or through a cannula 1 cm from the vessel wall. Considering the hydrodynamics, would it be better to sample...
17 July 2017 8,150 3 View
How is the sample prepared, and how it is it added to the dissolution equipment for dissolution testing of a dry syrup for oral suspension?
17 July 2017 1,508 5 View
How to select dissolution sample solution? I find that in some tests, the samples withdrawn from the vessel need to be diluted as part of the quantitative procedure.
13 July 2017 787 4 View
Typically, the rotation speed for USP Apparatus 2 is between 25 and 75 rpm. Can we increase this rotation speed to improve the accuracy of the dissolution method? I am working with a fixed...
13 July 2017 5,894 6 View
What dissolution medium can be used with poorly water-soluble drugs (BCS Class 2)? If the drug substance is not soluble in that medium, how should the standard solutions for the calibration curve...
13 July 2017 4,916 8 View
I am preparing a film containing asenapine maleate. How should I select the composition of the dissolution medium?
13 July 2017 5,261 3 View
I am working with a gastroretentive drug delivery system for a fixed combination product. Drug A has absorbance in 0.1 N HCl while drug B does not. Can I use two separate media for the fixed...
13 July 2017 5,061 1 View
Many analyst ran the dissolution method without the sinkers and justified that the sinker did not require them. Is this correct? Is it mandatory to use sinkers in the dissolution testing of capsules?
13 July 2017 6,315 3 View
In dissolution study, many times flow through dissolution study is used? What is the reason?
06 July 2017 430 3 View
In Preparation of Perfume, Its needed to use various solvent. Which one is ideal solvent for preparation of perfume.
04 July 2017 645 3 View
In dissolution test, there are different ways to maintain sink condition. Outline some methods.
02 July 2017 4,918 5 View
In preparation of an in situ gelling system, I am having difficulty in gel formation.
04 December 2013 2,461 1 View
In formulation of dosage form with oily material, I need to add thickening agent. Which is the best thickening agent?
04 December 2013 7,677 2 View
In some advertisements for dissolution equipment that use a heating jacket instead of a water bath to maintain the dissolution medium in the vessels at the appropriate temperature. Are they in...
01 January 1970 938 1 View
What are different strategies to prepare immediate relase dosage form with BCS CLass II drugs?
01 January 1970 5,213 4 View
