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Questions related from Terun Desai
There is increasing chatter that proteins in the ACE2 receptor binding domain are related to COVID-19 entering humans cells and subsequently infecting the host. Is there any evidence of ACE...
20 March 2020 6,757 8 View
I would like to analyse epigenetic changes in response to dietary phytochemical supplementation in humans. Can anyone explain if this is feasible and how would such analysis be conducted? Thanks.
29 March 2019 5,962 2 View
Does anyone have papers relating fasting insulin levels and associated CVD risks?
04 November 2018 4,399 3 View
Could you explain what the units for measuring the enzyme is. The ELISA I'm using measures in pg.mL But many papers I've seen use U/L however they are measuring ACE activity not protein...
11 September 2018 3,565 2 View
Does anyone have any data for fasting insulin concentrations in Metabolic Syndrome patients? There seems to be wide variability between studies.
15 August 2018 6,695 3 View
In humans will the sugar moiety be metabolised after cleavage of anthocyanins? Normally the aglycone is absorbed from the intestine, does the same happen to the sugar moiety?
13 August 2018 3,143 3 View
Does anyone have papers of human trials suggesting polyphenols act as synbiotics? Thanks
04 June 2018 9,517 5 View
What are the standard units for Urinary Malondialdehyde relative creatinine? Is it umol.g creatinine? umol.mmol creatinine?
31 May 2018 6,193 4 View
Can anyone provide papers or links to research conducted with supplementation of antioxidant vitamins A, C or E in humans with Metabolic Syndrome? Thanks
30 May 2018 8,122 5 View
Can anyone provide reasons for why you may want to include an isocaloric placebo in a placebo-controlled RCT examining cardio metabolic responses to a nutritional intervention. Strictly matching...
27 December 2017 7,252 0 View
Is it possible for insulin sensitivity to change within 5 hours of consuming an antioxidant nutritional intervention?
27 December 2017 383 6 View
Does stroke volume and diastolic BP have a positive linear correlation? Given greater pre-load and thus end-diastolic volume is it expected that diastolic BP would be reduced?
15 December 2017 9,559 4 View
I have data for systolic blood pressure over 6 time points for 11 people. Instead of showing the mean response curve, I would like to show individual responses for each person. A line graph...
14 December 2017 869 2 View
Does anyone have papers saying that repeated-measures ANOVA has sufficient robustness when analysing a non-normal dataset?
01 December 2017 8,039 1 View
I have a repeated-measures crossover study design with 3 treatment conditions, all measured across 7 time points. I would like to control for baseline for each treatment. As I understand, a...
31 October 2017 5,879 10 View
What are normal concentrations for serum insulin in Metabolic Syndrome patients?
23 October 2017 3,234 4 View
Excerpt from Kay, Mazza and Holub (2005) The parent anthocyanins represented only 32.0% [120.63 2.85 (nmol h)/L] of the total anthocyanins detected with 68.0% [256.02 5.23 (nmol h) identified...
11 October 2017 6,227 5 View
Does HOMA measure insulin sensitivity or resistance?
04 October 2017 7,456 3 View
In a clinical setting to measure fasting blood glucose, is it better to use serum or capillary blood?
03 October 2017 3,729 3 View
Does anyone know of any papers published looking at the effects of fasting (up to 8hrs) on plasma volume change in humans?
14 September 2017 4,671 1 View
Is it possible to correct serum samples for plasma volume change without using hematocrit? It was suggested that measuring calcium or potassium in the serum sample would help me correct for PVC.
14 September 2017 6,612 1 View
Avg daily intake anthocyanin intake in UK? Avg daily intake total polyphenol intake worldwide?
04 September 2017 5,112 4 View
Can someone explain how cyanidin-3-glucoside equivalents are calculated for total anthocyanin content?
03 July 2017 7,004 5 View
How likely is it that lipid profile will change within 5 hours of consuming an anthocyanin supplement? Are there any papers reporting acute lipid profile responses in Metabolic Syndrome...
25 May 2017 8,113 4 View
Biomarkers of oxidative stress which are water soluble. Unlike lipid hydroperoxides and 8-isoprostanes.
11 May 2017 5,502 0 View
For clinical nutrition RCTs research is it better to report standard deviation or standard error of the mean? I understand that Std Dev is a descriptive statistic only for the number of...
24 April 2017 9,295 9 View
I have a LoA of: -0.49±5.52 Does the mean difference indicate intra-individual variability and the standard deviation indicate inter-individual variability?
13 April 2017 4,328 0 View
A vasovagal response may be observed with needle phobia upon insertion of the needle therefore reducing blood pressure, heart rate, stroke volume and cardiac output. However a study (Finsterer,...
01 March 2017 1,458 7 View
Stability of anthocyanins is very low and they are rapidly absorbed and eliminated. Does anyone have any or know of papers that have assessed anthocyanin bioavailability in various forms such as...
21 February 2017 1,910 5 View
I'd like to conduct some chemical analysis on a nutritional product. Can anyone suggest sources where I may be able to apply for funding?
19 February 2017 8,161 0 View
It is possible to have PPAR in active and inactive forms. If an upregulation of PPAR mRNA is observed does this automatically mean that PPAR is in its active form?
17 February 2017 7,143 3 View
There is a link between mitochondrial dysfunction resulting in increased ROS production, however is the reverse relationship possible where ROS causes mitochondrial dysfunction?..How would this occur?
02 November 2016 1,086 2 View
Has anyone done research looking at blood based biomarkers during heat stress in humans?
28 October 2016 9,809 8 View
I have previously read a paper (which I am desperately trying to find!) which mentioned that dietary intake by as much as 3 days prior to the exercise can affect substrate oxidation and therefore...
15 August 2016 1,360 3 View
I would like to conduct a glucose tolerance test. Except I would also like to assess insulin. Rather than take multiple blood samples from venepuncture I would like to do finger tip sampling. Can...
28 July 2016 2,081 3 View
Either by immunoassay or enzymatic. And where can I purchase this assay from, preferably in the UK. Thanks
23 July 2016 5,940 3 View
I am currently looking at a nutritional intervention which I think may be inducing epigenetic changes. In order to confirm this, I would like to measure epigenentic biomarkers preferably from...
15 June 2016 2,601 3 View
I currently have an exercise protocol which has high inter and intra-individual variability. I am comparing a treatment to a placebo. Due to the high variance is it possible for me to control this...
03 May 2016 943 4 View
I have read papers (especially by Asker Jeukendrup) suggesting that FatMax occurs around 63% Vo2peak in trained athletes during cycling. However, what is the general figure for active but not...
05 March 2016 1,815 14 View
