I am currently looking at a nutritional intervention which I think may be inducing epigenetic changes.
In order to confirm this, I would like to measure epigenentic biomarkers preferably from blood samples?
Does anyone know if this is possible and are there any other techniques to assess epigenetic changes?
As such, it does not seem likely that one can provide a convincing evidence of epigenetic changes by studying blood samples if the cells in question are other than blood cells.
Tausif,
I am right in understanding that isolating blood cells would be feasible in assessing epigenetic changes?
I have attached a paper which may be of interest.
Do you know of any other techniques which could be used?
"I am right in understanding that isolating blood cells would be feasible in assessing epigenetic changes?"
Studying methylation state of DNA in blood cells will inform you of just that - state of methylation in the cells under study!
Establishing a causal relationship between changes or differences you may see between two groups will the key to providing a convincing evidence of your hypothesis.
[As you probably already know, a statistical association between one or a set of parameters is not a causal link. If it were, one could claim that ownership of a Lexus LS460 car causes reduction in infant mortality.]
- Badges
- Science topic
- Similar topics
- Chemistry
- Pharmacology
- Pharmaceuticals
- Drugs