hi dear

treat your tissue first with xylene, then wash it by ethanol , and treat it with SDS  

this research may help you

Hello. You can successfully adapt an extraction protocol using Trizol reagent, treating aproximatedly 10 slices of 10 um from paraffin-embedded tissues with Xilol and ethanol P.A., adding RNA lysis buffer and next follow the standard protocol for Trizol extraction. You can obtain both DNA and RNA from this method. 

Hi,

xylene treatment of tissue slices and subsequent proteanase K digestion will release the DNA from cells. Using silica based membranes for purifying nucleic acids will increases quality of purified DNA. 

Hi Lena,

Deparafinization by use of Xylene is necessary

You can use High Pure PCR Template Preparation Kit from Roche. Its perfect