I want to study cell signaling. where the protein synthesized from signal transduction by cell A is secreted and is important for signal transduction pathway to cell B. Plz suggest such 2 cell lines, where I can track its live progress.
Hi there,
It depends on the type of protein, you should read moreclearly about your protein.
1. different cells expressing the particular protein: You can use some databases like cell atlas or the past literature.
2. You can find the similar protein and its published information available that will guide you to look into the particular aspect.
As there are millions of cell lines available but you must seek which is required for the protein type. Hope it helps.
Something like interferon secretion sounds like it is what you are looking for. You can find some cells (e.g. PMDC05) that will secrete IFN upon TLR stimulation....and then most cells will respond to IFN where you will see many interferon stimulated genes
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