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Hi, I am currently working on a project where we examine the effect of an intervention on fatigue. The project has been carried out according to an one-group pre-test post-test design. I am...

20 February 2022 801 3 View

As far as I know, I can plot either -log10(p-values) on the y-axis of a volcano plot, or the -log10(adjusted p-values) after adjusting them for example with Benjamini-Hochberg. When plotting...

13 February 2022 3,575 3 View

Is it possible to run a correlation test on a continuous DV and a categorical IV with 3 levels? I'm investigating is gender is associated with academic procrastination, however, my gender...

12 February 2022 5,020 4 View

I have two treatment groups with 4 biological replicates each. I measured 100 lipid species in each of them and want to visualize the differences using a volcano plot. Which of these two ways is...

10 February 2022 9,457 3 View

I am performing a systematic review of prevalence studies. I have pooled prevalence rates using the program MetaXL (double arcsine transformation, random effects model) which gives me a point...

07 February 2022 9,311 7 View

Let us suppose that we have an intervention, for example technology integration in the science classroom. Can we study what mediators could affect the results of the intervention, for example...

05 February 2022 4,186 6 View

I have a question about determining the change in the decision reliability pre-post introduction of a system to support decision-making. I have designed a fully crossed study design where 5...

04 February 2022 7,963 3 View

EDIT: Please see below for the edited version of this question first (02.04.22) Hi, I am searching for a reliable normalization method. I have two chip-seq datas to be compared with t-test but...

31 January 2022 4,254 12 View

I have two different ChIP-seq data for different proteins, I have aligned them to some fragments in the DNA. Some of these fragments get zero read count for one of them or for both. To be able to...

31 January 2022 4,934 3 View

Hello, I want to cross-validate the RWR model using LOO-CV, I have obtained an RWR score between two nodes. Need suggestions on "data input" for LOO-CV and code for the same. Thanks in advance!

07 January 2022 8,106 1 View

I want to calculate the standard deviation for the mean reduction in a paired sample T test. I only have the mean measurements as well as the standard deviation for pre and post measurements, so...

22 December 2021 4,478 5 View

Dear Community, I am facing a rather odd problem. I am running an OLS multivariate regression, my independent variables change signs compared to signs of univariat regression, although VIF is...

06 December 2021 801 3 View

Dear Community, I was wondering whether it is possible or not to validate hypothesis testing based on OLS regression with 2 indep variables only? Or will such thing decrease the credibility of...

06 December 2021 2,029 7 View

Hi there! If I want to examine whether the variance of a sample changes significantly through a treatment, how would I do that? In this case I would not be interested in the change/difference...

04 December 2021 5,997 6 View

I have a set of data from wounds that are going through normal wound healing and those that have been treated to intentionally delay wound healing (n=3) in pigs. For normal/acute wounds, tissues...

29 November 2021 6,521 7 View

Hello, I have abundance data for bird surveys at various sites - for simplicity, let's say I did 10 surveys at each of 10 sites. When I use EstimateR() function in R, it gives me a Chao1 value...

17 November 2021 1,593 3 View

The aim of my research is to analyse the correlation between two delta values (change between two timepoints) via regression analysis. Let the variables be X, Y, and Z, and t0 represent...

15 November 2021 2,478 10 View

I am interested in statistically analyzing a non-normal distributed histogram of the performance of 141 test cases in the 0-200 range, with most of them concentrated in the 50-100 range and the...

10 November 2021 3,641 27 View

I have the following graph chosen mostly based on ColorBrewer. However, when output to 0% saturation or printed out, the colours look quite similar. Is there a good web tool for testing out colour...

03 November 2021 9,637 3 View

Can you kindly suggest the best statistical test to compare the yield of a protein from a bacterial culture carried out in different pH? Is one-way ANOVA a suitable method?

04 October 2021 2,565 4 View

I have two independent groups of animals (n=4 in each group) observed under two different conditions (A and B) at the same time of the day and equal time interval (12 hours). For each group,...

01 October 2021 7,327 20 View

Upon reading following paper: https://pubmed.ncbi.nlm.nih.gov/31727409/, I saw that the power analysis is based on a two-sample t-test, while the primary endpoint is based on ANCOVA analysis...

28 September 2021 8,573 6 View

Hello, I replicated a study in which participants are asked to rate the importance of some user experience dimensions (like efficiency, usefulness, perspicuity, etc.) for a product (0-7...

26 September 2021 9,500 5 View

Suppose Intervention A and Intervention B are randomly allocated to 50 participants each (n = 100) to compare their efficacy in preventing a condition after a certain time period. Efficacy is...

22 September 2021 1,193 8 View