NF-κB represents a central factor in inflammation, stress response, cell differentiation or proliferation as well as cell death.Furthermore, it regulates cytokine production and therefore, translocation of p65 into nucleus enhances inflammatory state.

how clean is your serum separation from platelets, etc?

There are a few papers on serum levels of NFkappaB but elevated levels seem to be connected to (or follow) histological changes. My interpretation is that serum levels of NFkappaB is a poor measurement of inflammation.

Nice Contribution Rikard G Fred