The mechanism of delayed apoptosis?

04 April 2016 1 2K Report

Hi everyone, I established a gene-knockout cell lines, and the cells suffered an apoptosis after 20 days culture. What's the potential basis for the late onset of apoptosis?

Go J Yoshida

NAD exhaustion due to poly-ADP-ribosylation is one of the mechanism of delayed apoptosis and necrosis.

Article Ha HC and Snyder SHPoly(ADP-ribose) polymerase is a mediator...

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